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美沙酮处方医师人数与医疗补助计划参保者美沙酮治疗使用和处方类阿片药物使用的关联。

Association of Buprenorphine-Waivered Physician Supply With Buprenorphine Treatment Use and Prescription Opioid Use in Medicaid Enrollees.

机构信息

Department of Health Management and Policy, University of Kentucky College of Public Health, Lexington.

Department of Health Policy and Management, Emory University Rollins School of Public Health, Atlanta, Georgia.

出版信息

JAMA Netw Open. 2018 Sep 7;1(5):e182943. doi: 10.1001/jamanetworkopen.2018.2943.

Abstract

IMPORTANCE

Expanding treatment for opioid addiction has been recognized as an essential component of a comprehensive national response to the opioid epidemic. The Drug Addiction Treatment Act and its amendments attempted to improve access to treatment by involving office-based physicians in the provision of buprenorphine treatment.

OBJECTIVES

To estimate the association of availability of buprenorphine-waivered physicians with buprenorphine treatment use and, secondarily, with prescription opioid use among Medicaid enrollees.

DESIGN, SETTING, AND PARTICIPANTS: This economic evaluation study used state-level panel data analysis to estimate the association between the number of buprenorphine-waivered physicians and the Medicaid-covered buprenorphine prescribing rate and opioid prescribing rate among Medicaid fee-for-service and managed care enrollees throughout the United States between January 1, 2011, and December 31, 2016.

MAIN OUTCOMES AND MEASURES

Buprenorphine prescribing rate and opioid prescribing rate, measured as the number of buprenorphine prescriptions and opioid prescriptions covered by Medicaid on a quarterly basis per 1000 enrollees.

RESULTS

The sample included 1059 quarterly observations. Two additional 100-patient-waivered physicians per 1 000 000 residents (approximately a 10% increase) were associated with an increase in the quarterly number of Medicaid-covered buprenorphine prescriptions of 0.46 (95% CI, 0.24-0.67) per 1000 enrollees and a reduction in the quarterly number of opioid prescriptions of 1.01 (95% CI, -1.87 to -0.15) per 1000 enrollees. Furthermore, 5 additional 30-patient-waivered physicians per 1 000 000 residents (approximately a 10% increase) were associated with an increase in the quarterly number of Medicaid-covered buprenorphine prescriptions of 0.37 (95% CI, 0.22-0.52) per 1000 enrollees and a reduction in the quarterly number of opioid prescriptions of 0.96 (95% CI, -1.85 to -0.07) per 1000 enrollees. A 10% increase in the number of buprenorphine-waivered physicians was associated with an approximately 10% increase in the Medicaid-covered buprenorphine prescribing rate and a 1.2% reduction in the opioid prescribing rate.

CONCLUSIONS AND RELEVANCE

Expanding capacity for buprenorphine treatment holds the potential to improve access to opioid addiction treatment, which may further reduce prescription opioid use and slow the ongoing opioid epidemic in the United States.

摘要

重要性

扩大阿片类药物成瘾治疗已被认为是应对阿片类药物流行的全面国家应对措施的重要组成部分。《药物成瘾治疗法》及其修正案试图通过让以门诊为基础的医生参与丁丙诺啡治疗,来改善治疗的可及性。

目的

评估有丁丙诺啡豁免权的医生的可用性与接受医疗补助的患者丁丙诺啡治疗使用的相关性,其次是与处方类阿片使用的相关性。

设计、设置和参与者:这项经济评估研究使用了州级面板数据分析,以评估 2011 年 1 月 1 日至 2016 年 12 月 31 日期间,美国全民医疗保障服务和管理式医疗参保者中,每 1000 名参保者中丁丙诺啡豁免医生的数量与医疗补助覆盖的丁丙诺啡开方率和阿片类药物开方率之间的关联。

主要结局和措施

丁丙诺啡开方率和阿片类药物开方率,以每 1000 名参保者每季度丁丙诺啡和阿片类药物处方的数量来衡量。

结果

样本包括 1059 个季度观察。每 100 万居民增加 2 名(约 10%)接受 100 名患者豁免的医生与每 1000 名参保者中医疗补助覆盖的丁丙诺啡处方数增加 0.46(95%置信区间,0.24-0.67)和每 1000 名参保者中阿片类药物处方数减少 1.01(95%置信区间,-1.87 至-0.15)有关。此外,每 100 万居民增加 5 名(约 10%)接受 30 名患者豁免的医生与每 1000 名参保者中医疗补助覆盖的丁丙诺啡处方数增加 0.37(95%置信区间,0.22-0.52)和每 1000 名参保者中阿片类药物处方数减少 0.96(95%置信区间,-1.85 至-0.07)有关。丁丙诺啡豁免医生人数增加 10%与医疗补助覆盖的丁丙诺啡开方率增加约 10%和阿片类药物开方率降低 1.2%有关。

结论和相关性

扩大丁丙诺啡治疗能力有可能改善阿片类药物成瘾治疗的可及性,这可能进一步减少处方类阿片类药物的使用,并减缓美国目前正在进行的阿片类药物流行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b310/6324514/fd4c3b760af6/jamanetwopen-1-e182943-g001.jpg

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