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[喀麦隆城市人口中引起出血热病毒的血清学研究]

[Serological study of the virus responsible for hemorrhagic fever in an urban population of Cameroon].

作者信息

Paix M A, Poveda J D, Malvy D, Bailly C, Merlin M, Fleury H J

机构信息

Laboratoire de Virologie, Université de Bordeaux II, France.

出版信息

Bull Soc Pathol Exot Filiales. 1988;81(4):679-82.

PMID:3064937
Abstract

A sero-epidemiological study of Hemorrhagic Fever Viruses in a urban population of Cameroon. The authors report the results of a sero-epidemiological survey undertaken in a urban population of Cameroon and concerning Congo, Rift (RVF), Lassa, Ebola, Marburg and Yellow Fever Viruses. On 375 human sera tested, 1.06% show antibodies against RVF virus and 1.87% are positive for anti-Ebola antibodies thus yielding evidence that these two viruses are present in this area of Cameroon. 33.75% have antibodies against Yellow Fever Virus as determined with an Hemagglutination-inhibition test. This quite high percentage, in spite of the weak specificity of the method for this virus, could raise the problem of the opportunity of a vaccination campaign. No antibody to Marburg, Lassa or Congo viruses is detected.

摘要

喀麦隆城市人口中出血热病毒的血清流行病学研究。作者报告了在喀麦隆城市人口中进行的一项血清流行病学调查结果,该调查涉及刚果热病毒、裂谷热病毒(RVF)、拉沙病毒、埃博拉病毒、马尔堡病毒和黄热病病毒。在检测的375份人类血清中,1.06%显示出抗RVF病毒抗体,1.87%的抗埃博拉病毒抗体呈阳性,从而证明这两种病毒存在于喀麦隆的这一地区。用血凝抑制试验测定,33.75%的人具有抗黄热病病毒抗体。尽管该方法对该病毒的特异性较弱,但这一相当高的比例可能会引发疫苗接种运动时机的问题。未检测到抗马尔堡病毒、拉沙病毒或刚果病毒的抗体。

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