氟拉那点涂溶液治疗自然感染猫的猫栉首蚤和耳螨混合感染的疗效
Efficacy of fluralaner spot-on solution for the treatment of Ctenocephalides felis and Otodectes cynotis mixed infestation in naturally infested cats.
作者信息
Bosco Antonio, Leone Federico, Vascone Rosachiara, Pennacchio Saverio, Ciuca Lavinia, Cringoli Giuseppe, Rinaldi Laura
机构信息
Department of Veterinary Medicine and Animal Production, University of Naples Federico II, Via Della Veterinaria 1, 80137, Naples, Italy.
Clinica Veterinaria Adriatica, Senigallia, Ancona, Italy.
出版信息
BMC Vet Res. 2019 Jan 16;15(1):28. doi: 10.1186/s12917-019-1775-2.
BACKGROUND
Cats can be infested with several ectoparasite species, especially Ctenocephalides felis and Otodectes cynotis. The aim of this study was to evaluate the efficacy of a single topical application of fluralaner against C. felis and O. cynotis natural infestation in stray (study 1) and owned (study 2) cats in central and southern Italy.
RESULTS
The number of live fleas found on each cat on Day 0 ranged from 1 to more than 30 (arithmetic mean live flea count = 11.9 in study 1; 14.6 in study 2) while no live fleas were found on days 7 and 84 post topical application of fluralaner. The number of live mites found on each cat on Day 0 ranged from 1 to 42 (arithmetic mean live mite count = 6.4 in study 1; 8.9 in study 2) while no live mites were found on days 7 and 84 post topical application of fluralaner.
CONCLUSIONS
Topical fluralaner completely eliminated fleas and ear mites from infested cats and was 100% effective against both parasites up to 84 days after treatment.
背景
猫可能感染多种体外寄生虫，尤其是猫栉首蚤和耳痒螨。本研究的目的是评估在意大利中部和南部对流浪猫（研究1）和家养猫（研究2）单次局部应用氟虫腈对猫栉首蚤和耳痒螨自然感染的疗效。
结果
在第0天，每只猫身上发现的活跳蚤数量从1只到30多只不等（研究1中活跳蚤计数的算术平均值 = 11.9；研究2中为14.6），而在局部应用氟虫腈后的第7天和第84天未发现活跳蚤。在第0天，每只猫身上发现的活螨数量从1只到42只不等（研究1中活螨计数的算术平均值 = 6.4；研究2中为8.9），而在局部应用氟虫腈后的第7天和第84天未发现活螨。
结论
局部应用氟虫腈可使受感染的猫完全清除跳蚤和耳螨，并且在治疗后长达84天对这两种寄生虫的杀灭效果达100%。
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