Burnouf Thibault, Guaguère Eric
Dermatology Referral Service, Clinique Vétérinaire Saint Bernard, F-59160 Lomme, Lille, France.
Can Vet J. 2025 Jun;66(6):663-676.
Otodectic mange is one of the most common ectoparasitic diseases in cats and the most common cause of feline otitis externa. It is particularly prevalent in young cats between 3 and 6 mo of age and is a veterinary concern, especially in catteries, due to its highly contagious nature. Although there is a risk of overdiagnosis if based solely on cerumen, it is not difficult to identify if there is a clinical suspicion in a young cat. Considering the variety of available acaricidal molecules, as well as the need to use the most effective treatment, the present article reviews evidence comparing various types of systemic treatment for otodectic mange in cats.
Isoxazolines (sarolaner, fluralaner, or esafoxolaner) or similar molecules such as tigolaner (a bispyrazole) and macrocyclic lactones (selamectin, eprinomectin, or moxidectin) can lead to parasitological cure and improvement of clinical signs associated with otodectic mange in cats, with rare, mainly cutaneous side effects with mild, autoresolving lesions.
Similarities in the clinical and parasitological efficacy of these substances highlight the need for comparative studies that could allow identification of the most efficacious product.
耳螨疥癣是猫最常见的外寄生虫病之一，也是猫外耳炎最常见的病因。它在3至6月龄的幼猫中尤为普遍，由于其高度传染性，在兽医领域备受关注，尤其是在猫舍。虽然仅根据耳垢存在过度诊断的风险，但如果对幼猫有临床怀疑，识别并不困难。考虑到可用杀螨分子的多样性，以及使用最有效治疗方法的必要性，本文综述了比较猫耳螨疥癣各种全身治疗方法的证据。
异恶唑啉类药物（沙罗拉纳、氟拉纳、或依沙氟拉纳）或类似分子如替戈拉纳（一种双吡唑）和大环内酯类药物（塞拉菌素、埃普利诺菌素、或莫昔克丁）可使感染耳螨疥癣的猫实现寄生虫学治愈，并改善相关临床症状，主要是罕见的皮肤副作用，病变轻微且可自行消退。
这些物质在临床和寄生虫学疗效上的相似性凸显了开展比较研究的必要性，以便确定最有效的产品。
