Hyun B H, Gulati G L, Ashton J K
Thomas Jefferson University Medical School, Philadelphia, Pennsylvania.
Hematol Oncol Clin North Am. 1988 Dec;2(4):513-23.
Proper evaluation of the bone marrow requires adequate sampling, appropriate specimen processing, sufficient clinical history, and review of representative blood smears and pertinent laboratory data. Aspiration and needle biopsy should be performed at the same time routinely. Aspirate smears, touch preparations from the biopsy, and sections from the aspirate and biopsy should be processed appropriately and examined in a systematic fashion to perform a comprehensive evaluation considered essential to arrive at or rule out a diagnosis, or as an adjunct in the management of patients, particularly those undergoing chemotherapy and/or radiotherapy.
对骨髓进行恰当评估需要足够的采样、合适的标本处理、充分的临床病史,以及对有代表性的血涂片和相关实验室数据的审查。通常应同时进行抽吸和针吸活检。抽吸涂片、活检组织的触片以及抽吸物和活检组织的切片都应进行适当处理,并以系统的方式进行检查,以进行全面评估,这被认为是得出或排除诊断的关键,或者作为患者管理的辅助手段,特别是对那些正在接受化疗和/或放疗的患者。