Ridgeway Greg, Nørgaard Mette, Rasmussen Thomas Bøjer, Finkle William D, Pedersen Lars, Bøtker Hans Erik, Sørensen Henrik Toft
Department of Criminology, University of Pennsylvania, Philadelphia, PA, USA,
Department of Statistics, University of Pennsylvania, Philadelphia, PA, USA,
Clin Epidemiol. 2019 Jan 4;11:67-80. doi: 10.2147/CLEP.S189263. eCollection 2019.
The aim of this study was to examine hospital performance measures that account more comprehensively for unique mixes of patients' characteristics.
Nationwide cohort registry-based study within a population-based health care system.
In this study, 331,513 patients discharged with a primary cardiovascular diagnosis from 1 of 26 Danish hospitals during 2011-2015 were included. Data covering all Danish hospitals were drawn from the Danish National Patient Registry and the Danish National Health Service Prescription Database.
Thirty-day post-admission mortality rates, 30-day post-discharge readmission rates, and the associated numbers needed to harm were measured.
For each index hospital, we used a non-parametric logistic regression model to compute propensity scores. Propensity score weighted patients treated at other hospitals collectively resembled patients treated at the index hospital in terms of age, sex, primary discharge diagnosis, diagnosis history, medications, previous cardiac procedures, and comorbidities. Outcomes for the weighted patients treated at other hospitals formed benchmarks for the index hospital. Doubly robust regression formally tested whether the outcomes of patients at the index hospital differed from the outcomes of the patients used to form the benchmarks. For each index hospital, we computed the false discovery rate, ie, the probability of being incorrect if we claimed the hospital differed from its benchmark.
Five hospitals exceeded their benchmark for 30-day mortality rates, with the number needed to harm ranging between 55 and 137. Seven hospitals exceeded their benchmark for readmission, with the number needed to harm ranging from 22 to 71. Our benchmarking approach flagged fewer hospitals as outliers compared with conventional regression methods.
Conventional methods flag more hospitals as outliers than our benchmarking approach. Our benchmarking approach accounts more thoroughly for differences in hospitals' patient case mix, reducing the risk of false-positive selection of suspected outliers. A more comprehensive system of hospital performance measurement could be based on this approach.
本研究旨在探讨能更全面考虑患者特征独特组合的医院绩效指标。
在基于人群的医疗保健系统内进行的全国队列登记研究。
本研究纳入了2011年至2015年期间从丹麦26家医院中的1家出院且主要诊断为心血管疾病的331,513名患者。涵盖所有丹麦医院的数据来自丹麦国家患者登记处和丹麦国家卫生服务处方数据库。
测量入院后30天死亡率、出院后30天再入院率以及相关的伤害所需人数。
对于每家索引医院,我们使用非参数逻辑回归模型计算倾向得分。倾向得分加权后,其他医院治疗的患者在年龄、性别、主要出院诊断、诊断史、用药情况、既往心脏手术和合并症方面总体上与索引医院治疗的患者相似。其他医院治疗的加权患者的结局构成了索引医院的基准。双重稳健回归正式检验索引医院患者的结局是否与用于形成基准的患者结局不同。对于每家索引医院,我们计算了错误发现率,即如果我们声称该医院与其基准不同时出错的概率。
5家医院的30天死亡率超过了其基准,伤害所需人数在55至137之间。7家医院的再入院率超过了其基准,伤害所需人数在22至71之间。与传统回归方法相比,我们的基准化方法将较少的医院标记为异常值。
与我们的基准化方法相比,传统方法将更多医院标记为异常值。我们的基准化方法更全面地考虑了医院患者病例组合的差异,降低了疑似异常值假阳性选择的风险。基于此方法可以建立一个更全面的医院绩效评估系统。