Universidade Federal do Rio Grande do Sul (UFRGS), Programa de Pós Graduação em Ciências Médicas (PPGCM), Rua Ramiro Barcelos 2400, segundo andar, Porto Alegre, 90035-903, Brazil.
Department of Rheumatology, Hospital de Clinicas de Porto Alegre, Rua Ramiro Barcelos 2350, sexto andar, Porto Alegre, 90035-903, Brazil.
Adv Rheumatol. 2018 May 24;58(1):1. doi: 10.1186/s42358-018-0001-4.
To assess the main fears and beliefs of people with rheumatoid arthritis (RA) and their effect on treatment outcomes; METHODS: A systematic literature review was conducted in Pubmed/Medline; original articles published up to May 2017, reporting fears and/or beliefs of adult patients with RA were analyzed. Fears and beliefs were collected by two independent researchers and grouped into categories.
Among 474 references identified, 84 were analyzed, corresponding to 24,336 RA patients. Fears were reported in 38.4% of the articles (N = 32/84): most studies described fears related to pharmacological therapy (50.0%, N = 16/32) and fear of disability (28.1%, N = 9/32). Beliefs were reported in 88.0% of articles (N = 74/84) and were found to moderate the patient-perceived impact of RA in 44.6% (N = 33/74), mainly the emotional impact (18.9%, N = 14/74); measures of function, quality of life, fatigue and pain were also found to be affected by patients' beliefs in 8.1% (N = 6/74), 6.8% (N = 5/74), 2.7% (N = 2/74) and 2.7% (N = 2/74) of the articles, respectively. Beliefs about therapy were linked to adherence in 17.6% of articles (N = 13/74) and beliefs about cause of RA predicted coping patterns in 12.2% of publications (N = 9/74). Only 9.5% (N = 8/84) of articles reported fears and/or beliefs of patients living outside Europe and North America: there was only one work which recruited patients in Latin America and no article included patients from Africa.
In RA, patients' beliefs are linked to impact of disease and non-adherence. Further research is needed on fears/ beliefs of patients living outside Europe and North America.
评估类风湿关节炎（RA）患者的主要恐惧和信念及其对治疗结果的影响；方法：在 Pubmed/Medline 上进行了系统的文献回顾；分析了截至 2017 年 5 月发表的报告成人 RA 患者恐惧和/或信念的原始文章。两名独立研究人员收集了恐惧和信念，并将其分为几类。
在 474 篇参考文献中，有 84 篇被分析，涉及 24336 例 RA 患者。38.4%的文章（N=32/84）报告了恐惧：大多数研究描述了与药物治疗相关的恐惧（50.0%，N=16/32）和对残疾的恐惧（28.1%，N=9/32）。88.0%的文章（N=74/84）报告了信念，并发现信念在 44.6%（N=33/74）的情况下可以调节患者对 RA 的感知影响，主要是对情绪的影响（18.9%，N=14/74）；还发现功能、生活质量、疲劳和疼痛的测量值也受到患者信念的影响，分别占 8.1%（N=6/74）、6.8%（N=5/74）、2.7%（N=2/74）和 2.7%（N=2/74）的文章。治疗信念与依从性相关的文章占 17.6%（N=13/74），RA 发病原因的信念预测了 12.2%的文献（N=9/74）中的应对模式。只有 9.5%（N=8/84）的文章报告了欧洲和北美以外地区患者的恐惧和/或信念：只有一篇文章招募了拉丁美洲的患者，没有一篇文章包括非洲的患者。
在 RA 中，患者的信念与疾病的影响和不依从性有关。需要对欧洲和北美以外地区患者的恐惧/信念进行进一步研究。
