Institute of Food Science and Human Nutrition, Leibniz University Hannover, Am Kleinen Felde 30, 30167, Hannover, Germany.
German Nutrition Society (DGE), Godesberger Allee 18, 53175, Bonn, Germany.
Mol Nutr Food Res. 2019 Mar;63(6):e1801178. doi: 10.1002/mnfr.201801178. Epub 2019 Jan 28.
The nutrition societies of Germany, Austria, and Switzerland are the joint editors of the "D-A-CH reference values for nutrient intake", which are revised regularly.
By reviewing vitamin-B -related biomarker studies, the reference values for vitamin B were revised in 2018. For adults, the estimated intake is based on the adequate serum concentrations of holotranscobalamin and methylmalonic acid. The estimated values for children and adolescents are extrapolated from the adult reference value by considering differences in body mass, an allometric exponent, and growth factors. For infants below 4 months of age, an estimated value is set based on the vitamin B intake via breast milk. The reference values for pregnant and lactating women consider the requirements for the fetus and for loss via breast milk. The estimated values for vitamin B intake for infants, children, and adolescents range from 0.5 to 4.0 µg d . For adults, the estimated values are set at 4.0 µg d , and for pregnant and lactating women, they are set at 4.5 and 5.5 µg d , respectively.
Based on the data of several vitamin B status biomarkers studies, the reference value for vitamin B intake for adults is raised from 3.0 to 4.0 µg d .
德国、奥地利和瑞士的营养学会是《德奥瑞营养素摄入量参考值》的联合编辑者，该参考值定期修订。
通过审查与维生素 B 相关的生物标志物研究，2018 年修订了维生素 B 的参考值。对于成年人，估计摄入量基于全钴胺素和甲基丙二酸的充足血清浓度。对于儿童和青少年，通过考虑体重、比例指数和生长因素的差异，从成人参考值推断得出估计值。对于 4 个月以下的婴儿，根据通过母乳摄入的维生素 B 设定了一个估计值。对于孕妇和哺乳期妇女，参考值考虑了胎儿的需求以及通过母乳的损失。婴儿、儿童和青少年的维生素 B 摄入量估计值范围为 0.5 至 4.0 µg/d。对于成年人，估计值设定为 4.0 µg/d，对于孕妇和哺乳期妇女，分别设定为 4.5 和 5.5 µg/d。
基于几项维生素 B 状态生物标志物研究的数据，成年人的维生素 B 摄入量参考值从 3.0 提高到 4.0 µg/d。
