Belfiore Anna, Palmieri Vincenzo Ostilio, Di Gennaro Carla, Settimo Enrica, De Sario Maria Grazia, Lattanzio Stefania, Fanelli Margherita, Portincasa Piero
Clinica Medica "A. Murri", Department of Biomedical Sciences and Human Oncology, University of Bari Medical School, Bari, Italy.
Biostatistic, Interdisciplinary Department of Medicine, University of Bari Medical School, Bari, Italy.
Intern Emerg Med. 2020 Jan;15(1):49-58. doi: 10.1007/s11739-019-02024-4. Epub 2019 Jan 18.
Chronic heart failure (CHF) is one of the main disabilities in elderly patients requiring frequent hospitalizations with high health care costs. We studied the outcome of CHF outpatient management in reducing hospitalization after discharge from a division of Internal Medicine at a large 3rd referral regional Hospital. 147 CHF inpatients (M:F: 63:84; mean age 76 ± 9.6 years) admitted for acute exacerbation of CHF were followed up as outpatients at 1, 6, 12 and 24 months after discharge. At baseline, patients underwent: laboratory tests, ECG, echocardiogram and a dedicated-intensive health care educational program involving also their families. The rate of hospitalization in the same group of patients was compared with data from the previous 24 months, a period when patients had been seen elsewhere without disease management programs. Patients had high prevalence of comorbidities and the majority was in NYHA class III or IV. Hypertension and valvular heart disease were the most common causes for CHF. Systolic function was preserved (LVEF ≥ 50%) in 61.9% of cases. Functional NYHA class improved significantly after 6 months and remained stable at 24 months. There was a significant increase in the use of the renin-angiotensin system blockers, beta-blockers and diuretics compared to admission to the ward. At 24 months, hospital readmissions were decreased by 42% as compared to the previous 24 months. Risk factors for re-hospitalizations were anemia, NYHA class III or IV and previous hospitalizations. Establishing an intensive outpatient management program for CHF patients leads to long-term beneficial effects with improved clinical parameters and decreased hospitalization in the setting of Internal Medicine.
慢性心力衰竭(CHF)是老年患者的主要致残疾病之一,需要频繁住院,医疗费用高昂。我们研究了一家大型三级转诊区域医院内科某科室对CHF患者出院后进行门诊管理以减少住院率的效果。147例因CHF急性加重入院的患者(男∶女=63∶84;平均年龄76±9.6岁)在出院后1、6、12和24个月接受门诊随访。基线时,患者接受了实验室检查、心电图、超声心动图检查,并参加了一项专门的强化医疗保健教育计划,其家人也参与其中。将同一组患者的住院率与之前24个月的数据进行比较,在之前那段时间患者在其他地方就诊,没有疾病管理计划。患者合并症患病率高,大多数为纽约心脏协会(NYHA)心功能Ⅲ级或Ⅳ级。高血压和瓣膜性心脏病是CHF最常见的病因。61.9%的病例收缩功能得以保留(左心室射血分数[LVEF]≥50%)。NYHA功能分级在6个月后显著改善,并在24个月时保持稳定。与入院时相比,肾素 - 血管紧张素系统阻滞剂、β受体阻滞剂和利尿剂的使用显著增加。在24个月时,与之前24个月相比,再次入院率降低了42%。再次住院的危险因素包括贫血、NYHA心功能Ⅲ级或Ⅳ级以及既往住院史。为CHF患者建立强化门诊管理计划可产生长期有益效果,改善临床参数,并降低内科环境下的住院率。