Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
Graduate University of Science and Technology, VAST, Hanoi, Vietnam.
Nat Prod Res. 2020 May;34(9):1276-1281. doi: 10.1080/14786419.2018.1560290. Epub 2019 Jan 24.
Using various chromatographic separations, three new acylated flavonoid glycosides, namely barringosides G-I (-), were isolated from the water-soluble extract of branches and leaves. The structure elucidation was performed by extensive analysis of the 1D and 2D NMR and HR-QTOF-MS data. Of the isolated compounds, barringoside I () showed moderate inhibitory effects on LPS-induced NO production in RAW264.7 cells with an IC of 52.48 ± 1.04 µM.
采用各种色谱分离方法，从枝叶水溶性提取物中分离得到三种新的酰化黄酮苷，分别为 barringosides G-I(-)。通过对 1D 和 2D NMR 及 HR-QTOF-MS 数据的综合分析，完成了其结构鉴定。在所分离的化合物中，barringoside I()对 LPS 诱导的 RAW264.7 细胞中 NO 生成具有中等抑制作用，IC 为 52.48 ± 1.04 μM。
