Kolbe Katharina, Veleti Sri Kumar, Reiling Norbert, Lindhorst Thisbe K
Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, 33 North Drive, Bethesda, 20892, MD, United States.
Microbial Interface Biology, Research Center Borstel, Leibniz Lung Center, Parkallee 22, 23845 Borstel, Germany.
Beilstein J Org Chem. 2019 Jan 2;15:1-15. doi: 10.3762/bjoc.15.1. eCollection 2019.
The importance of bacterial lectins for adhesion, pathogenicity, and biofilm formation is well established for many Gram-positive and Gram-negative bacteria. However, there is very little information available about lectins of the tuberculosis-causing bacterium, (). In this paper we review previous studies on the carbohydrate-binding characteristics of mycobacteria and related proteins, discussing their potential relevance to infection and pathogenesis.
许多革兰氏阳性菌和革兰氏阴性菌中,细菌凝集素在黏附、致病性和生物膜形成方面的重要性已得到充分证实。然而,关于导致结核病的细菌()的凝集素,现有的信息非常少。在本文中,我们回顾了先前关于分枝杆菌和相关蛋白质碳水化合物结合特性的研究,讨论了它们与感染和发病机制的潜在相关性。