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工程化石墨烯氧化物与超小 SPIONs 及智能药物释放用于癌症治疗。

Engineering graphene oxide with ultrasmall SPIONs and smart drug release for cancer theranostics.

机构信息

Country State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, 1295 Ding-Xi Road, Shanghai 200050, P. R. China.

出版信息

Chem Commun (Camb). 2019 Feb 7;55(13):1963-1966. doi: 10.1039/c8cc09185d.

Abstract

A smart nanotheranostics nanoplatform was constructed using engineered graphene oxide and the in situ growth of ultrasmall superparamagnetic iron oxide particles (SPIONs). The construction of such a novel theranostics nanoplatform shows great potential in tumor theranostics, especially for T1-weighted magnetic resonance (T1-MR) imaging guided, pH-sensitive chemotherapy.

摘要

采用工程化氧化石墨烯和超小超顺磁性氧化铁粒子(SPION)的原位生长构建了一种智能的纳米诊疗一体化纳米平台。这种新型诊疗一体化纳米平台的构建在肿瘤诊疗中具有很大的潜力,特别是在 T1 加权磁共振(T1-MR)成像引导、pH 敏感化疗方面。

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