An epidemiologic study of pelvic organ prolapse in rural Chinese women: a population-based sample in China.

INTRODUCTION AND HYPOTHESIS

We aimed to investigate the prevalence and risk factors of symptomatic pelvic organ prolapse (POP) in rural China.

METHODS

A cross-sectional study of POP was conducted in rural China from February 2014 to March 2016. In total, 25,864 rural women were recruited. All were asked to complete a questionnaire that included questions about their age, job, parity, diseases, and so on. Symptomatic POP was assessed using Pelvic Organ Prolapse Quantification (POP-Q) system staging and validation questionnaires. Multivariate logistic regression was used to assess the factors associated with symptomatic POP.

RESULTS

The prevalence of symptomatic POP was 9.10%. There was a consistent trend toward an increasing prevalence of POP with increasing age, ranging from 2.53 to 13.40% (P < 0.0001). Women aged 50-59 years [adjusted odds ratio (AOR) 1.86, 95% confidence interval (CI) 1.46-2.37] were more likely to have POP than women aged 20-29 years. POP was positively associated with giving birth to more than three children (AOR 2.18, 95% CI 1.88-2.43). Cesarean section was a significant protective factor (AOR = 0.34, 95% CI 0.33-0.49) compared with vaginal delivery. Multivariate logistic regression analysis showed that obesity, constipation, smoking, coughing, gynecological diseases, and other physical diseases were also associated with POP.

CONCLUSIONS

Symptomatic POP affects a substantial proportion of women in rural China. Older age, multiparity, vaginal delivery, obesity, and many chronic conditions significantly increased the odds of developing symptomatic POP. Additional healthcare campaigns are needed to educate women in rural areas about POP.