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酒精对空间亮度对比敏感度的短期影响。

Short-term influence of alcohol on spatial brightness contrast sensitivity.

作者信息

Zulauf M, Flammer J, Signer C

机构信息

Augenklinik, Kantonsspital, Luzern, Schweiz.

出版信息

Ophthalmologica. 1988;197(3):159-65. doi: 10.1159/000309937.

Abstract

The present crossover, controlled study demonstrates that alcohol at a blood concentration of approximately 0.08% reduces the contrast sensitivity (p less than 0.001). The mean contrast sensitivity was 15.03 dB in the control measurements and 14.39 dB in the measurements with alcohol. Brightness contrast sensitivity was measured with white, green, red and blue light, in this sequence. Therefore, the test design may present time effects as well as 'color effects'. The mean decrease in contrast sensitivity was with white light -1.26 dB, with green light -0.88 dB and with red light -0.57 dB. Contrast sensitivity tested with blue light showed even a slight increase with alcohol (+0.12 dB). The time interval between alcohol consumption and the test was important (p less than 0.001). The mean decrease in contrast sensitivity with alcohol in subjects with a short interval of 40 min was less reduced (-0.3 dB) than in subjects with a long interval of 60 min (-0.98 dB). In summary, at moderate doses of alcohol, contrast sensitivity is only moderately decreased and this decrease depends on the time between alcohol consumption and the test.

摘要

当前的交叉对照研究表明,血液浓度约为0.08%的酒精会降低对比敏感度(p<0.001)。对照测量时的平均对比敏感度为15.03dB,饮酒测量时为14.39dB。按照此顺序,使用白色、绿色、红色和蓝色光测量亮度对比敏感度。因此,测试设计可能存在时间效应以及“颜色效应”。白光下对比敏感度平均下降-1.26dB,绿光下为-0.88dB,红光下为-0.57dB。蓝光测试的对比敏感度在饮酒时甚至略有增加(+0.12dB)。饮酒与测试之间的时间间隔很重要(p<0.001)。间隔40分钟的受试者饮酒后对比敏感度平均下降幅度(-0.3dB)小于间隔60分钟的受试者(-0.98dB)。总之,中等剂量的酒精只会使对比敏感度适度降低,且这种降低取决于饮酒与测试之间的时间。

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