Associated Eye Care, University of Minnesota, Stillwater, Texas, USA; Alcon Laboratories, Inc., Fort Worth, Texas, USA.
Alcon Laboratories, Inc., Fort Worth, Texas, USA.
J Cataract Refract Surg. 2019 Apr;45(4):501-506. doi: 10.1016/j.jcrs.2018.10.043. Epub 2019 Jan 25.
To compare mechanical characteristics and stability of Clareon CNA0T0 intraocular lens (IOL) with 4 currently marketed monofocal IOLs and to evaluate axial displacement and simulated dioptric power shift using a range of compression diameters.
Alcon Laboratories, Inc., Fort Worth, Texas, USA.
Experimental study.
Clareon CNA0T0, AcrySof SN60WF, enVista MX60, Tecnis ZCB00, and Vivinex iSert XY1 IOLs (10 per group) were assessed using standardized methods for axial displacement, optic decentration, and optic tilt per the International Organization for Standardization ISO11979-3. Axial displacement was also measured over a range of compression diameters (9.0 to 11.0 mm).
At 10.0 mm compression, the mean axial displacement for the CNA0T0 IOL (0.02 mm ± 0.01 [SD]) was significantly lower than for the MX60, ZCB00, and XY1 IOLs (P < .005). At all compression diameters, the CNA0T0 and SN60WF IOLs had the lowest levels of axial displacement and corresponding simulated dioptric power shift at the corneal plane versus other IOL models. At 10.0 mm compression, the mean optic decentration was within ±0.06 mm for all models, and there were no significant differences between the CNA0T0 IOL and other IOLs. At 10.0 mm compression, the mean optic tilt was no greater than 1.2 degrees for all IOL models evaluated; however, the mean optic tilt for the CNA0T0 IOL was significantly lower than for the MX60 IOL (P < .005).
The CNA0T0 and SN60WF IOLs showed the lowest levels of axial displacement and corresponding simulated dioptric power shift over all tested compression diameters, indicating they might provide the most consistent refractive outcomes.
比较 Clareon CNA0T0 人工晶状体（IOL）与 4 种目前市售的单焦点 IOL 的机械特性和稳定性，并评估在一系列压缩直径下的轴向位移和模拟屈光度移位。
美国德克萨斯州沃思堡市爱尔康实验室公司。
实验研究。
使用标准化方法评估 Clareon CNA0T0、AcrySof SN60WF、enVista MX60、Tecnis ZCB00 和 Vivinex iSert XY1 IOL（每组 10 个）的轴向位移、光学偏心和光学倾斜，符合国际标准化组织 ISO11979-3 标准。还在 9.0 至 11.0mm 的一系列压缩直径下测量轴向位移。
在 10.0mm 压缩时，CNA0T0 IOL（0.02mm±0.01[SD]）的平均轴向位移明显低于 MX60、ZCB00 和 XY1 IOL（P<.005）。在所有压缩直径下，CNA0T0 和 SN60WF IOL 在角膜平面处的轴向位移和相应的模拟屈光度移位最低，与其他 IOL 模型相比。在 10.0mm 压缩时，所有模型的平均光学偏心均在±0.06mm 以内，CNA0T0 IOL 与其他 IOL 之间无显著差异。在 10.0mm 压缩时，评估的所有 IOL 模型的平均光学倾斜均不超过 1.2 度；然而，CNA0T0 IOL 的平均光学倾斜明显低于 MX60 IOL（P<.005）。
在所有测试的压缩直径下，CNA0T0 和 SN60WF IOL 显示出最低的轴向位移和相应的模拟屈光度移位，这表明它们可能提供最一致的屈光结果。
