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新型疏水一体式人工晶状体的囊袋性能

Capsular Bag Performance of a Novel Hydrophobic Single-Piece Intraocular Lens.

作者信息

Waser Klemens, Straßmair Klaus, Pomberger Leon, Khalil Haidar, Laubichler Peter, Bolz Matthias, Hirnschall Nino

机构信息

Kepler University Clinic, Krankenhausstraße 9, 4020, Linz, Austria.

Johannes Kepler University, Linz, Austria.

出版信息

Ophthalmol Ther. 2025 Feb;14(2):295-308. doi: 10.1007/s40123-024-01075-x. Epub 2024 Dec 12.

DOI:10.1007/s40123-024-01075-x
PMID:39666249
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11754762/
Abstract

INTRODUCTION

We conducted an evaluation of capsular bag performance of the Clareon CNA0T0 intraocular lens (IOL), focusing on postoperative anterior chamber depth (ACD), IOL tilt, and IOL decentration.

METHODS

Inclusion criteria were bilateral age-related cataract and the ability to provide informed consent. Exclusion criteria were prior surgeries, combined surgeries, and conditions posing a risk for postoperative capsular bag instability. Preoperative and 8-week postoperative assessments included optical biometry and high-resolution anterior segment optical coherence tomography (OCT). Subjective refraction was conducted only at 8 weeks postoperative visit.

RESULTS

In the first analysis, 49 right eyes of 49 patients were included. Mean preoperative and postoperative ACD were 3.10 and 4.69 mm, respectively. Mean preoperative tilt was 4.77°, increasing to 5.06° postoperatively. Preoperative decentration was 0.16 mm, increasing to 0.26 mm postoperatively. Absolute refractive error (ARE) was + 0.31D, with 81% of eyes within ± 0.5D limits. In analysis II (98 eyes of 49 patients), both eyes showed a moderate correlation in IOL tilt (Pearson correlation coefficient: 0.27, p = 0.061) and a low correlation in IOL decentration (Pearson correlation coefficient: 0.02, p = 0.892) and ARE (Spearman: 0.15, p = 305) between right and left eyes of the same patient.

CONCLUSIONS

The Clareon CNA0T0 IOL demonstrated high mechanical stability, with low postoperative tilt and decentration values, resulting in excellent refractive outcomes and visual acuity. These findings confirm the IOL's high stability within the capsular bag and effectiveness in minimizing postoperative refractive error, requiring only minor A-constant adjustments for optimal cataract surgery outcomes.

TRIAL REGISTRATION

NCT06595693.

摘要

引言

我们对Clareon CNA0T0人工晶状体（IOL）的囊袋性能进行了评估，重点关注术后前房深度（ACD）、IOL倾斜度和IOL偏心度。

方法

纳入标准为双侧年龄相关性白内障且能提供知情同意书。排除标准为既往手术史、联合手术以及存在术后囊袋不稳定风险的情况。术前和术后8周评估包括光学生物测量和高分辨率眼前节光学相干断层扫描（OCT）。仅在术后8周复诊时进行主观验光。

结果

在首次分析中，纳入了49例患者的49只右眼。术前和术后平均ACD分别为3.10和4.69毫米。术前平均倾斜度为4.77°，术后增加到5.06°。术前偏心度为0.16毫米，术后增加到0.26毫米。绝对屈光误差（ARE）为+0.31D，81%的眼睛在±0.5D范围内。在分析II（49例患者的98只眼）中，同一患者的右眼和左眼在IOL倾斜度（Pearson相关系数：0.27，p = 0.061）、IOL偏心度（Pearson相关系数：0.02，p = 0.892）和ARE（Spearman：0.15，p = 0.305）方面均显示出中度相关性。

结论

Clareon CNA0T0 IOL表现出高机械稳定性，术后倾斜度和偏心度值较低，从而产生了优异的屈光结果和视力。这些发现证实了IOL在囊袋内的高稳定性以及在最小化术后屈光误差方面的有效性，仅需对A常数进行微小调整即可获得最佳白内障手术效果。

试验注册

NCT06595693。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/8cd6d944de8e/40123_2024_1075_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/45494c90d3f3/40123_2024_1075_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/34e5445ccb40/40123_2024_1075_Fig2_HTML.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/90fe4a5ff964/40123_2024_1075_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/49efd59c3ed8/40123_2024_1075_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/3b86de37c07c/40123_2024_1075_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/21670f9a8ace/40123_2024_1075_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/8cd6d944de8e/40123_2024_1075_Fig8_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/45494c90d3f3/40123_2024_1075_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/34e5445ccb40/40123_2024_1075_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/ae59d8e4fc4f/40123_2024_1075_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/90fe4a5ff964/40123_2024_1075_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/49efd59c3ed8/40123_2024_1075_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/3b86de37c07c/40123_2024_1075_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/21670f9a8ace/40123_2024_1075_Fig7_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5750/11754762/8cd6d944de8e/40123_2024_1075_Fig8_HTML.jpg

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J Cataract Refract Surg. 2022 Nov 1;48(11):1318-1324. doi: 10.1097/j.jcrs.0000000000000997. Epub 2022 Jun 27.
4
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5
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