El Hadi Hamza, Di Vincenzo Angelo, Vettor Roberto, Rossato Marco
Internal Medicine 3, Department of Medicine, University of Padua, Padua, Italy.
Front Physiol. 2019 Jan 11;9:1954. doi: 10.3389/fphys.2018.01954. eCollection 2018.
Obesity is the consequence of chronic positive energy balance and considered a leading risk factor for cardiovascular and metabolic diseases. Due to its epidemic trends among children and adults, there is an increasing interest in implementing new therapeutic interventions to tackle overweight and obesity. Activation of brown adipose tissue (BAT) represents today a promising strategy to enhance energy expenditure (EE) through heat production. More recently, "browning" of white adipose tissue (WAT) has gained increasing attention in research area as an alternative method in stimulating energy dissipation. This minireview aims to summarize the current knowledge of some dietary compounds that have been shown to promote BAT activation and WAT browning with subsequent beneficial health effects.
肥胖是慢性正能量平衡的结果,被认为是心血管和代谢疾病的主要危险因素。由于其在儿童和成人中的流行趋势,人们对实施新的治疗干预措施来解决超重和肥胖问题的兴趣日益浓厚。激活棕色脂肪组织(BAT)如今是一种通过产热来增加能量消耗(EE)的有前景的策略。最近,白色脂肪组织(WAT)的“褐色化”作为刺激能量消耗的一种替代方法,在研究领域越来越受到关注。本综述旨在总结一些已被证明能促进BAT激活和WAT褐色化并随后产生有益健康影响的膳食化合物的现有知识。