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Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor?

作者信息

Anastasilakis Athanasios D, Polyzos Stergios A, Makras Polyzois, Douni Eleni, Mantzoros Christos S

机构信息

Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece.

First Department of Pharmacology, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.

出版信息

Metabolism. 2019 Apr;93:100-102. doi: 10.1016/j.metabol.2019.01.013. Epub 2019 Jan 25.

DOI:10.1016/j.metabol.2019.01.013
PMID:30690037
Abstract
摘要

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1
Irisin: good or bad for the bone? A new path forward after the reported discovery of irisin receptor?鸢尾素:对骨骼有益还是有害?在报道发现鸢尾素受体后开启的新方向?
Metabolism. 2019 Apr;93:100-102. doi: 10.1016/j.metabol.2019.01.013. Epub 2019 Jan 25.
2
Irisin as a regulator of bone and glucose metabolism.鸢尾素作为骨代谢和糖代谢的调节因子。
Minerva Endocrinol. 2018 Dec;43(4):489-500. doi: 10.23736/S0391-1977.17.02779-1. Epub 2017 Nov 20.
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The effect of Irisin on bone cells in vivo and in vitro.鸢尾素对体内和体外骨细胞的影响。
Biochem Soc Trans. 2021 Feb 26;49(1):477-484. doi: 10.1042/BST20200978.
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The Irisin Hormone Profile and Expression in Human Bone Tissue in the Bone Healing Process in Patients.人骨组织中骨愈合过程中鸢尾素激素谱及表达
Med Sci Monit. 2017 Sep 4;23:4278-4283. doi: 10.12659/msm.906293.
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High irisin levels are associated with better glycemic control and bone health in children with Type 1 diabetes.高鸢尾素水平与 1 型糖尿病患儿更好的血糖控制和骨骼健康相关。
Diabetes Res Clin Pract. 2018 Jul;141:10-17. doi: 10.1016/j.diabres.2018.03.046. Epub 2018 Apr 19.
6
Crosstalk Between Muscle and Bone Via the Muscle-Myokine Irisin.肌肉与骨骼通过肌肉分泌因子鸢尾素的相互作用。
Curr Osteoporos Rep. 2016 Aug;14(4):132-7. doi: 10.1007/s11914-016-0313-4.
7
Irisin: 'fat' or artefact.鸢尾素:“脂肪”还是假象?
Clin Endocrinol (Oxf). 2015 Apr;82(4):467-74. doi: 10.1111/cen.12627. Epub 2014 Nov 7.
8
A review on irisin, a new protagonist that mediates muscle-adipose-bone-neuron connectivity.综述鸢尾素:一种介导肌肉-脂肪-骨骼-神经元连接的新主角。
Eur Rev Med Pharmacol Sci. 2017 Oct;21(20):4687-4693.
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Irisin, a unique non-inflammatory myokine in stimulating skeletal muscle metabolism.鸢尾素,一种在刺激骨骼肌代谢方面独特的非炎性肌动蛋白。 (注:原文中“myokine”可能有误,正确的是“myokine”,常见释义为“肌动蛋白” ,但根据语境这里可能是“鸢尾素是一种独特的非炎性肌因子,可刺激骨骼肌代谢” ,翻译仅供参考,你可根据实际情况调整 )
J Physiol Biochem. 2015 Dec;71(4):679-89. doi: 10.1007/s13105-015-0433-9. Epub 2015 Sep 23.
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The production, detection, and origin of irisin and its effect on bone cells.鸢尾素的产生、检测及其来源及其对骨细胞的作用。
Int J Biol Macromol. 2021 May 1;178:316-324. doi: 10.1016/j.ijbiomac.2021.02.181. Epub 2021 Feb 27.

引用本文的文献

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In patients with anorexia nervosa, myokine levels are altered but are not associated with bone mineral density loss and bone turnover alteration.在神经性厌食症患者中,肌动蛋白水平发生改变,但与骨矿物质密度降低和骨转换改变无关。
Endocr Connect. 2022 May 10;11(5):e210488. doi: 10.1530/EC-21-0488.
2
Plasma Concentration of Irisin and Brain-Derived-Neurotrophic Factor and Their Association With the Level of Erythrocyte Adenine Nucleotides in Response to Long-Term Endurance Training at Rest and After a Single Bout of Exercise.静息状态及单次运动后长期耐力训练对鸢尾素和脑源性神经营养因子血浆浓度及其与红细胞腺嘌呤核苷酸水平相关性的影响
Front Physiol. 2020 Jul 31;11:923. doi: 10.3389/fphys.2020.00923. eCollection 2020.