Islam Aminul, Stenos John, Vincent Gemma, Graves Stephen
Australian Rickettsial Reference Laboratory, University Hospital Geelong, Geelong, Victoria 3220, Australia.
New South Wales Health Pathology, Nepean Hospital, Penrith, NSW 2751, Australia.
Trop Med Infect Dis. 2019 Jan 25;4(1):18. doi: 10.3390/tropicalmed4010018.
This small study reports on a non-pyrogenic response of five different Australian isolates of ( . They were all members of Genomic Group IV and obtained from three cases of acute human infection, one case of chronic human infection and one case of goat abortion. The guinea pigs infected with these isolates did not develop fever (temperature ≥40.0 °C), which is consistent with other members of this genomic group that were isolated from elsewhere in the world. In contrast, guinea pigs infected with the classical USA tick isolate, Nine Mile phase 1 (RSA 493) of Genomic Group I, experienced a four-day febrile period.
这项小型研究报告了五株不同的澳大利亚 ( )分离株的无热原反应。它们均属于基因组IV群,分别来自三例急性人类感染病例、一例慢性人类感染病例和一例山羊流产病例。感染这些分离株的豚鼠未出现发热(体温≥40.0°C),这与从世界其他地方分离出的该基因组群的其他成员一致。相比之下,感染基因组I群的经典美国蜱分离株九英里1期(RSA 493)的豚鼠经历了为期四天的发热期。