Ayhan Ziya, Yaman Aylin
Dokuz Eylul University Faculty of Medicine, Eye Diseases, İzmir, Turkey.
Noro Psikiyatr Ars. 2018;55(Suppl 1):S37-S40. doi: 10.29399/npa.23327.
Visual dysfunction is one of the most common clinical manifestations of multiple sclerosis (MS). For example, optic neuritis is the onset symptom in 20% of patients with MS. Visual pathway impairment presents in most patients with MS, including patients who have not experienced optic neuritis. During the last decade, many clinical trials of MS have included visual outcomes. One tool used in these studies, optical coherence tomography, is a non-contact, noninvasive, high-resolution optical imaging technology that helps segmentation and measurement of specific retinal layers using computerized algorithms. Optical coherence tomography is used in various stages of MS from diagnosis to treatment of the disease. In this review, we summarize the use of optical coherence tomography in MS and study its usefulness for evaluating the physical disabilities of MS patients.
视觉功能障碍是多发性硬化症（MS）最常见的临床表现之一。例如，视神经炎是20%的MS患者的首发症状。大多数MS患者都存在视觉通路损害，包括那些未曾经历过视神经炎的患者。在过去十年中，许多MS临床试验都纳入了视觉结果。这些研究中使用的一种工具，光学相干断层扫描，是一种非接触、非侵入性的高分辨率光学成像技术，它利用计算机算法帮助对特定视网膜层进行分割和测量。光学相干断层扫描在MS从诊断到治疗的各个阶段都有应用。在本综述中，我们总结了光学相干断层扫描在MS中的应用，并研究其对评估MS患者身体残疾状况的有用性。
