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罗马尼亚东北部一只意大利赛古吉奥犬的症状性利什曼病:病例报告

Symptomatic Leishmaniasis in an Italian Segugio Dog from Northeastern Romania: A Case Report.

作者信息

Tanase Oana Irina, Daraban Constantin, Velescu Elena, Boghean Dragos, Bocaneti-Daraban Florentina

机构信息

Dept. of Public Health and Molecular Biology Laboratory, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine Ion Ionescu de la Brad, Iasi, Romania.

Univet Clinic, Iasi, Romania.

出版信息

Iran J Parasitol. 2018 Oct-Dec;13(4):673-678.

Abstract

Leishmaniasis is a zoonotic parasitosis caused by a diphasic protozoan of the genus . The dogs are considered the main domestic reservoir of and its transmission occurs mainly through sand flies. We report the case of a 10 yr old Italian Segugio dog in Mar 2016 from Iasi County-Moldova Region, northeastern Romania, referred to a private clinic with progressive weight loss, dermal lesions over the muzzle, foot pads and over the right and left tarsal joints. The dog was born in Torino, Italy and transferred to Romania, with a history of regular travelling between these two countries. The physical examination revealed multiple cutaneous lesions with alopecia together with polyarthritis, lymphadenopathies, fatigue and weight loss. Neither fever or nor diarrhea were observed. The serological test (enzyme-linked immunosorbent assay) showed a positive result for Leishmaniasis. Light microscopy of the stained smears prepared from popliteal lymph node puncture failed to identify the amastigotes. The infection was treated using pentavalent antimonial therapy for eight weeks and Allopurinol for eight months. After nine months follow-up the dog presented with an improved body condition and no signs of recurrence.

摘要

利什曼病是一种由利什曼原虫属的双相原生动物引起的人畜共患寄生虫病。狗被认为是利什曼原虫的主要家养宿主,其传播主要通过白蛉。我们报告了一例2016年3月来自罗马尼亚东北部摩尔多瓦地区雅西县的10岁意大利塞古吉奥犬病例,该犬被转诊至一家私人诊所,有进行性体重减轻、口鼻部、脚垫以及左右跗关节处的皮肤病变。这只狗出生于意大利都灵,后被转移至罗马尼亚,有在这两个国家之间定期旅行的历史。体格检查发现多处皮肤病变伴脱毛,同时还有多关节炎、淋巴结病、乏力和体重减轻。未观察到发热或腹泻。血清学检测(酶联免疫吸附测定)显示利什曼病呈阳性结果。对腘窝淋巴结穿刺制备的染色涂片进行光学显微镜检查未能识别出无鞭毛体。使用五价锑疗法治疗感染八周,并使用别嘌呤醇治疗八个月。经过九个月的随访,这只狗身体状况有所改善,且无复发迹象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f3f/6348206/bea72ce82e2f/IJPA-13-673-g001.jpg

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