Thomas Devon N, Asarian Armand, Xiao Philip
Department of Surgery, The Brooklyn Hospital Center, Brooklyn, NY 11201, USA.
Department of Pathology, The Brooklyn Hospital Center, Brooklyn, NY 11201, USA.
J Surg Case Rep. 2019 Jan 24;2019(1):rjy355. doi: 10.1093/jscr/rjy355. eCollection 2019 Jan.
Adenoid cystic carcinoma of the breast (ACC) is a rare tumor, comprising <0.1% of all breast cancers. It has a unique dual-cell pattern and is indistinguishable from ACC arising from salivary tissue. It is a low-grade tumor with favorable prognosis, and rare metastasis, with unique features. It is more commonly seen in older women with a mean age at diagnosis of 63, with Caucasian women being at greatest risk. Most cases present as a painful, palpable mass in the outer quadrants of the breast, and must be diagnosed via core needle biopsy or surgical excisional biopsy. Although few other cancers resemble ACC it is commonly misdiagnosed. Given the rarity of this cancer, treatment guidelines have yet to be well established. Current treatment is focused around surgical resection, however, there are not specific recommendations for the extent of resection due to the lack of cases to draw from.
乳腺腺样囊性癌（ACC）是一种罕见的肿瘤，占所有乳腺癌的比例不到0.1%。它具有独特的双细胞模式，与涎腺组织来源的ACC难以区分。它是一种低级别肿瘤，预后良好，转移罕见，具有独特特征。它更常见于老年女性，诊断时的平均年龄为63岁，白种女性风险最高。大多数病例表现为乳腺外象限疼痛、可触及的肿块，必须通过粗针活检或手术切除活检进行诊断。尽管很少有其他癌症与ACC相似，但它常被误诊。鉴于这种癌症的罕见性，治疗指南尚未完善确立。目前的治疗主要围绕手术切除，然而，由于缺乏可供参考的病例，对于切除范围没有具体建议。
