• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Differential roles of Stella in the modulation of DNA methylation during oocyte and zygotic development.

作者信息

Han Longsen, Ren Chao, Zhang Jun, Shu Wenjie, Wang Qiang

机构信息

1State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, Jiangsu 211166 China.

2Department of Biotechnology, Beijing Institute of Radiation Medicine, Beijing, 100850 China.

出版信息

Cell Discov. 2019 Jan 29;5:9. doi: 10.1038/s41421-019-0081-2. eCollection 2019.

DOI:10.1038/s41421-019-0081-2
PMID:30701082
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6349861/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c36/6349861/733f496cd14d/41421_2019_81_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c36/6349861/733f496cd14d/41421_2019_81_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c36/6349861/733f496cd14d/41421_2019_81_Fig1_HTML.jpg

相似文献

1
Differential roles of Stella in the modulation of DNA methylation during oocyte and zygotic development.斯特拉在卵母细胞和合子发育过程中对DNA甲基化调控中的不同作用。
Cell Discov. 2019 Jan 29;5:9. doi: 10.1038/s41421-019-0081-2. eCollection 2019.
2
Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1.斯特拉通过防止 DNMT1 介导的从头甲基化来保护卵母细胞的甲基组。
Nature. 2018 Dec;564(7734):136-140. doi: 10.1038/s41586-018-0751-5. Epub 2018 Nov 28.
3
Inhibition of maintenance DNA methylation by Stella.斯黛拉对维持性DNA甲基化的抑制作用。
Biochem Biophys Res Commun. 2014 Oct 24;453(3):455-60. doi: 10.1016/j.bbrc.2014.09.101. Epub 2014 Oct 1.
4
DNA methylation and miRNA-1296 act in concert to mediate spatiotemporal expression of KPNA7 during bovine oocyte and early embryonic development.DNA甲基化与miRNA-1296协同作用，在牛卵母细胞和早期胚胎发育过程中介导KPNA7的时空表达。
BMC Dev Biol. 2019 Dec 2;19(1):23. doi: 10.1186/s12861-019-0204-x.
5
PGC7/Stella protects against DNA demethylation in early embryogenesis.PGC7/Stella在早期胚胎发育过程中可防止DNA去甲基化。
Nat Cell Biol. 2007 Jan;9(1):64-71. doi: 10.1038/ncb1519. Epub 2006 Dec 3.
6
Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.小鼠卵母细胞中广泛的组蛋白H3K4me3结构域调节母源-合子转变。
Nature. 2016 Sep 22;537(7621):548-552. doi: 10.1038/nature19360. Epub 2016 Sep 14.
7
Relationship between oocyte maturation and fertilization on zygotic diversity in swine.猪卵母细胞成熟与受精对合子多样性的影响
J Anim Sci. 1990 Jul;68(7):2027-33. doi: 10.2527/1990.6872027x.
8
The expression patterns of DNA methylation reprogramming related genes are associated with the developmental competence of cloned embryos after zygotic genome activation in pigs.DNA甲基化重编程相关基因的表达模式与猪合子基因组激活后克隆胚胎的发育能力相关。
Gene Expr Patterns. 2015 May-Jul;18(1-2):1-7. doi: 10.1016/j.gep.2015.04.001. Epub 2015 Apr 24.
9
Differential acetylation of histone H4 lysine during development of in vitro fertilized, cloned and parthenogenetically activated bovine embryos.体外受精、克隆及孤雌激活牛胚胎发育过程中组蛋白H4赖氨酸的差异乙酰化作用
Epigenetics. 2008 Jul-Aug;3(4):199-209. doi: 10.4161/epi.3.4.6497. Epub 2008 Jul 24.
10
Use of Chemicals to Inhibit DNA Replication, Transcription, and Protein Synthesis to Study Zygotic Genome Activation.使用化学物质抑制DNA复制、转录和蛋白质合成以研究合子基因组激活
Methods Mol Biol. 2017;1605:191-205. doi: 10.1007/978-1-4939-6988-3_13.

引用本文的文献

1
Divergent DNA methylation dynamics in marsupial and eutherian embryos.有袋类和真兽类胚胎中不同的DNA甲基化动态变化。
Nature. 2025 May 14. doi: 10.1038/s41586-025-08992-2.
2
Defining ortholog-specific UHRF1 inhibition by STELLA for cancer therapy.通过STELLA定义用于癌症治疗的直系同源物特异性UHRF1抑制作用。
Nat Commun. 2025 Jan 8;16(1):474. doi: 10.1038/s41467-024-55481-7.
3
The global phosphorylation landscape of mouse oocytes during meiotic maturation.小鼠卵母细胞减数分裂成熟过程中的全球磷酸化图谱。

本文引用的文献

1
Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1.斯特拉通过防止 DNMT1 介导的从头甲基化来保护卵母细胞的甲基组。
Nature. 2018 Dec;564(7734):136-140. doi: 10.1038/s41586-018-0751-5. Epub 2018 Nov 28.
2
Cytoplasmic cleavage of DPPA3 is required for intracellular trafficking and cleavage-stage development in mice.DPPA3 的细胞质裂解对于小鼠的细胞内运输和卵裂期发育是必需的。
Nat Commun. 2017 Nov 21;8(1):1643. doi: 10.1038/s41467-017-01387-6.
3
De novo DNA methylation drives 5hmC accumulation in mouse zygotes.
EMBO J. 2024 Oct;43(20):4752-4785. doi: 10.1038/s44318-024-00222-1. Epub 2024 Sep 10.
4
TET enzyme driven epigenetic reprogramming in early embryos and its implication on long-term health.TET酶驱动早期胚胎中的表观遗传重编程及其对长期健康的影响。
Front Cell Dev Biol. 2024 Aug 1;12:1358649. doi: 10.3389/fcell.2024.1358649. eCollection 2024.
5
DPPA3 facilitates genome-wide DNA demethylation in mouse primordial germ cells.DPPA3 促进小鼠原始生殖细胞中的全基因组 DNA 去甲基化。
BMC Genomics. 2024 Apr 5;25(1):344. doi: 10.1186/s12864-024-10192-7.
6
Molecular mechanisms underlying totipotency.全能性的分子机制。
Life Sci Alliance. 2023 Sep 4;6(11). doi: 10.26508/lsa.202302225. Print 2023 Nov.
7
Epigenetic reprogramming during the maternal-to-zygotic transition.母源-合子转变过程中的表观遗传重编程。
MedComm (2020). 2023 Aug 2;4(4):e331. doi: 10.1002/mco2.331. eCollection 2023 Aug.
8
Oocyte Aging: A Multifactorial Phenomenon in A Unique Cell.卵母细胞衰老：一种独特细胞中的多因素现象。
Aging Dis. 2024 Feb 1;15(1):5-21. doi: 10.14336/AD.2023.0527.
9
PGC7 Regulates Genome-Wide DNA Methylation by Regulating ERK-Mediated Subcellular Localization of DNMT1.PGC7 通过调控 ERK 介导的 DNMT1 亚细胞定位来调节全基因组 DNA 甲基化。
Int J Mol Sci. 2023 Feb 4;24(4):3093. doi: 10.3390/ijms24043093.
10
Regulation of paternal 5mC oxidation and H3K9me2 asymmetry by ERK1/2 in mouse zygotes.ERK1/2 对小鼠受精卵中父本 5mC 氧化和 H3K9me2 不对称性的调控
Cell Biosci. 2022 Mar 7;12(1):25. doi: 10.1186/s13578-022-00758-x.
从头DNA甲基化驱动小鼠受精卵中5-羟甲基胞嘧啶（5hmC）的积累。
Nat Cell Biol. 2016 Feb;18(2):225-233. doi: 10.1038/ncb3296. Epub 2016 Jan 11.
4
Dppa3 expression is critical for generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting.Dppa3表达对于完全重编程的诱导多能干细胞的产生以及Dlk1-Dio3印记的维持至关重要。
Nat Commun. 2015 Jan 23;6:6008. doi: 10.1038/ncomms7008.
5
Inhibition of maintenance DNA methylation by Stella.斯黛拉对维持性DNA甲基化的抑制作用。
Biochem Biophys Res Commun. 2014 Oct 24;453(3):455-60. doi: 10.1016/j.bbrc.2014.09.101. Epub 2014 Oct 1.
6
Programming and inheritance of parental DNA methylomes in mammals.哺乳动物中亲本 DNA 甲基组的编程和遗传。
Cell. 2014 May 8;157(4):979-991. doi: 10.1016/j.cell.2014.04.017.
7
PGC7 binds histone H3K9me2 to protect against conversion of 5mC to 5hmC in early embryos.PGC7 通过结合组蛋白 H3K9me2 来防止早期胚胎中 5mC 向 5hmC 的转化。
Nature. 2012 Jun 3;486(7403):415-9. doi: 10.1038/nature11093.
8
PGC7/Stella protects against DNA demethylation in early embryogenesis.PGC7/Stella在早期胚胎发育过程中可防止DNA去甲基化。
Nat Cell Biol. 2007 Jan;9(1):64-71. doi: 10.1038/ncb1519. Epub 2006 Dec 3.
9
Dppa3 / Pgc7 / stella is a maternal factor and is not required for germ cell specification in mice.Dppa3 / Pgc7 / Stella是一种母体因子，在小鼠生殖细胞特化过程中并非必需。
BMC Dev Biol. 2004 Feb 23;4:2. doi: 10.1186/1471-213X-4-2.
10
Stella is a maternal effect gene required for normal early development in mice.斯特拉是小鼠正常早期发育所需的母体效应基因。
Curr Biol. 2003 Dec 2;13(23):2110-7. doi: 10.1016/j.cub.2003.11.026.