桔青霉全基因组测序揭示了霉菌毒素桔霉素的生物合成基因簇。
Whole-Genome Sequencing of the Fungus Penicillium citrinum Reveals the Biosynthesis Gene Cluster for the Mycotoxin Citrinin.
作者信息
Schmidt-Heydt Markus, Stoll Dominic, Geisen Rolf
机构信息
Department of Safety and Quality of Fruit and Vegetables, Max Rubner-Institut, Federal Research Institute of Nutrition and Food, Karlsruhe, Germany.
出版信息
Microbiol Resour Announc. 2019 Jan 24;8(4). doi: 10.1128/MRA.01419-18. eCollection 2019 Jan.
Abstract
Penicillium citrinum is a food-contaminating ascomycete that consistently produces large amounts of the mycotoxin citrinin. Citrinin exhibits, besides its toxicity, antibiotic effects and thus potentially forces antibiotic resistance. Within the genome sequence, we identified the biosynthesis gene cluster for citrinin, which appears to be highly conserved within the genus .
摘要
桔青霉是一种污染食品的子囊菌，能持续产生大量的桔霉素霉菌毒素。桔霉素除了具有毒性外，还具有抗生素作用，因此可能会导致抗生素耐药性。在基因组序列中，我们鉴定出了桔霉素的生物合成基因簇，该基因簇在该属中似乎高度保守。
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