Department of Psychiatry & Research Support Centre, University of Zimbabwe, Harare, Zimbabwe.
BMC Pregnancy Childbirth. 2019 Jan 31;19(1):53. doi: 10.1186/s12884-019-2193-y.
Depression is a common psychiatric disorder that is highly prevalent among people living with HIV (PLWH). Depression is linked to poor adherence to anti-retroviral medication while in the peri-natal period may affect birth outcomes. Intimate partner violence (IPV) has been linked to depression. Little is known about the factors associated with depression in HIV positive pregnant women in Zimbabwe.
We carried out a cross-sectional study in 4 busy primary care clinics offering antenatal services during the months of June through to September in 2016. Simple random sampling was used to screen HIV positive pregnant women while they waited to be attended to at each clinic. Eligible women who gave written informed consent were screened using a locally validated screening tool-the Edinburgh Postnatal Depression Scale (EPDS).
A total of 198(85%) participants were recruited out of 234 that were approached. The mean age of participants was 26.6(SD 4.5), of these, 176 (88.9%) had secondary education or more. A total of 78 (39.4%) (95% CI 32.5-46.3) met criteria for antenatal depression according to the local version of the EPDS. Factors associated with antenatal depression after multivariate analysis were intimate partner violence (IPV) [OR 3.2 (95% CI 1.5-6.7)] and previous history of depression OR 4.1 (95% CI 2.0-8.0)].
The prevalence of antenatal depression among HIV positive pregnant women in primary care clinics is high. Factors associated with antenatal depression in pregnant HIV positive women are IPV and previous history of depression. There is need for routine screening for depression during the antenatal period and interventions targeting depression in this population should include components to address IPV.
抑郁症是一种常见的精神疾病,在 HIV 感染者(PLWH)中发病率很高。抑郁症与抗逆转录病毒药物治疗期间的依从性差有关,而在围产期可能会影响出生结局。亲密伴侣暴力(IPV)与抑郁症有关。在津巴布韦,人们对 HIV 阳性孕妇中与抑郁症相关的因素知之甚少。
我们在 2016 年 6 月至 9 月期间在 4 家繁忙的初级保健诊所进行了一项横断面研究,这些诊所提供产前服务。在每个诊所等待就诊时,采用简单随机抽样法对 HIV 阳性孕妇进行筛查。对书面知情同意的合格妇女使用经过当地验证的筛查工具——爱丁堡产后抑郁量表(EPDS)进行筛查。
在接触的 234 名孕妇中,共有 198 名(85%)符合条件。参与者的平均年龄为 26.6(SD 4.5),其中 176 名(88.9%)接受过中学或更高水平的教育。根据 EPDS 的当地版本,共有 78 名(39.4%)(95%CI 32.5-46.3)符合产前抑郁症的标准。多变量分析后与产前抑郁症相关的因素是亲密伴侣暴力(IPV)[OR 3.2(95%CI 1.5-6.7)]和以前有抑郁史[OR 4.1(95%CI 2.0-8.0)]。
初级保健诊所中 HIV 阳性孕妇产前抑郁症的患病率很高。与 HIV 阳性孕妇产前抑郁症相关的因素是 IPV 和以前有抑郁史。需要在产前期间常规筛查抑郁症,针对该人群的抑郁症干预措施应包括解决 IPV 的内容。