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减肥手术对肥胖患者肠道微生物群的影响:文献综述

The effects of bariatric surgery on gut microbiota in patients with obesity: a review of the literature.

作者信息

Ulker İzzet, Yildiran Hilal

机构信息

Department of Nutrition and Dietetics, Faculty of Health Sciences, Gazi University, Besevler, Ankara, Turkey.

出版信息

Biosci Microbiota Food Health. 2019;38(1):3-9. doi: 10.12938/bmfh.18-018. Epub 2018 Oct 27.

DOI:10.12938/bmfh.18-018
PMID:30705797
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6343052/
Abstract

Obesity is a disease with a rapidly increasing prevalence all over the world in recent years. Genetic and environmental factors are involved in the etiology of obesity, and the effect of microbiota on obesity is becoming increasingly clear. Obesity treatment has various treatment modalities such as behavior modification, medical nutrition therapy, physical activity enhancement, and surgical intervention. When other treatment methods are not successful, bariatric surgery is usually resorted to as the treatment method. Some changes such as food choices, the level of hormones and enzymes due to anatomical changes, pH of the stomach, and microbiota are observed after bariatric surgery. Alteration in the microbiota composition after bariatric surgery has also been reported to be important in achieving body weight loss and preserving body weight loss.

摘要

肥胖是一种近年来在全球患病率迅速上升的疾病。肥胖的病因涉及遗传和环境因素,微生物群对肥胖的影响也日益明显。肥胖治疗有多种方式,如行为改变、医学营养治疗、增加体育活动和手术干预。当其他治疗方法无效时,通常会采用减肥手术作为治疗手段。减肥手术后会观察到一些变化,如食物选择、解剖结构改变导致的激素和酶水平、胃的pH值以及微生物群的变化。据报道,减肥手术后微生物群组成的改变对于实现体重减轻和维持体重减轻也很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6f5/6343052/e55471615bfb/bmfh-38-003-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6f5/6343052/e55471615bfb/bmfh-38-003-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6f5/6343052/e55471615bfb/bmfh-38-003-g001.jpg

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Weight-loss interventions and gut microbiota changes in overweight and obese patients: a systematic review.超重和肥胖患者的减肥干预措施和肠道微生物群变化:系统评价。
超越体重减轻:探索减肥手术后肠道微生物群改变的神经学后果。
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