Pietersz R N, Reesink H W, Huijgens P C, van Oers M H
Red Cross Blood Bank, Amsterdam, The Netherlands.
Vox Sang. 1988;55(3):129-32. doi: 10.1111/j.1423-0410.1988.tb05078.x.
To study survival and function of leukocyte-poor platelet concentrates (lp-PC) prepared from buffy coats, random platelet transfusions requested for thrombocytopenic patients were evaluated. The lp-PC issued were stored at 22 degrees C for either 1, 3 or 5 days before transfusion. From 31 transfusions, posttransfusion corrected count increments (CCI), corrected for body surface (m2) and divided by number of platelets transfused (1011), were calculated. The mean +/- SEM of the 1-, 24- and 48- hour CCI was 12.2 +/- 0.45, 11.2 +/- 0.51 and 8.8 +/- 0.58, respectively. No significant differences in CCI 24 h after transfusion were observed for 1p-PC stored for 1, 3 or 5 days. Hemostatic activity was observed in all 9 evaluable patients. It is concluded that platelets from 1p-PC survive well in patients, regardless of storage for 1, 3 or 5 days and that the platelets are hemostatically active after transfusion.
为研究从 Buffy 层制备的少白细胞血小板浓缩物（lp - PC）的存活情况和功能，对血小板减少症患者随机输注血小板的情况进行了评估。发放的 lp - PC 在输注前于 22℃储存 1、3 或 5 天。在 31 次输注中，计算了输血后校正计数增加值（CCI），校正了体表面积（m²）并除以输注的血小板数量（10¹¹）。1 小时、24 小时和 48 小时 CCI 的平均值±标准误分别为 12.2±0.45、11.2±0.51 和 8.8±0.58。储存 1、3 或 5 天的 lp - PC 在输血后 24 小时的 CCI 未观察到显著差异。在所有 9 名可评估患者中均观察到止血活性。得出的结论是，lp - PC 中的血小板在患者体内存活良好，无论储存 1、3 或 5 天，并且这些血小板在输血后具有止血活性。
