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本文引用的文献

1
Primary cardiac manifestation of autosomal dominant polycystic kidney disease revealed by patient induced pluripotent stem cell-derived cardiomyocytes.常染色体显性遗传多囊肾病的心脏首发表现：患者诱导多能干细胞衍生心肌细胞。
EBioMedicine. 2019 Feb;40:675-684. doi: 10.1016/j.ebiom.2019.01.011. Epub 2019 Jan 11.
2
Evaluation of variability in human kidney organoids.人类肾类器官的变异性评估。
Nat Methods. 2019 Jan;16(1):79-87. doi: 10.1038/s41592-018-0253-2. Epub 2018 Dec 20.
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Reproducibility of Molecular Phenotypes after Long-Term Differentiation to Human iPSC-Derived Neurons: A Multi-Site Omics Study.长期分化为人诱导多能干细胞源性神经元后的分子表型再现性：多中心组学研究。
Stem Cell Reports. 2018 Oct 9;11(4):897-911. doi: 10.1016/j.stemcr.2018.08.013. Epub 2018 Sep 20.
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Kidney Organoids: A Translational Journey.肾类器官：一段转化之旅。
Trends Mol Med. 2017 Mar;23(3):246-263. doi: 10.1016/j.molmed.2017.01.001. Epub 2017 Feb 7.
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Epigenetic Variation between Human Induced Pluripotent Stem Cell Lines Is an Indicator of Differentiation Capacity.人诱导多能干细胞系之间的表观遗传变异是分化能力的指标。
Cell Stem Cell. 2016 Sep 1;19(3):341-54. doi: 10.1016/j.stem.2016.06.019. Epub 2016 Jul 28.
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Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids.利用源自人多能性上胚层球体的CRISPR突变肾类器官对肾脏疾病进行建模。
Nat Commun. 2015 Oct 23;6:8715. doi: 10.1038/ncomms9715.
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Nephron organoids derived from human pluripotent stem cells model kidney development and injury.源自人类多能干细胞的肾单位类器官可模拟肾脏发育和损伤。
Nat Biotechnol. 2015 Nov;33(11):1193-200. doi: 10.1038/nbt.3392.
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Polycystin-1 Is a Cardiomyocyte Mechanosensor That Governs L-Type Ca2+ Channel Protein Stability.多囊蛋白-1是一种心肌细胞机械传感器，可调节L型钙通道蛋白的稳定性。
Circulation. 2015 Jun 16;131(24):2131-42. doi: 10.1161/CIRCULATIONAHA.114.013537. Epub 2015 Apr 17.
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Multiplex genome engineering using CRISPR/Cas systems.利用 CRISPR/Cas 系统进行多重基因组工程。
Science. 2013 Feb 15;339(6121):819-23. doi: 10.1126/science.1231143. Epub 2013 Jan 3.
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Induction of pluripotent stem cells from adult human fibroblasts by defined factors.通过特定因子将成人成纤维细胞诱导为多能干细胞。
Cell. 2007 Nov 30;131(5):861-72. doi: 10.1016/j.cell.2007.11.019.

Revealing potential cardiac manifestation of ADPKD using iPS cell-derived cardiomyocytes.

作者信息

Morizane Ryuji

机构信息

Renal Division, Brigham and Women's Hospital, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA, USA; Harvard Stem Cell Institute, Cambridge, MA, USA; Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, MA, USA.

出版信息

EBioMedicine. 2019 Feb;40:19-20. doi: 10.1016/j.ebiom.2019.01.049. Epub 2019 Jan 31.

DOI:10.1016/j.ebiom.2019.01.049
PMID:30711518
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6413538/
Abstract
摘要