1980年至2012年间瑞典国家癌症登记处未发现脑肿瘤发病率增加的证据。
No Evidence for Increased Brain Tumour Incidence in the Swedish National Cancer Register Between Years 1980-2012.
作者信息
Nilsson Jonas, Järås Jacob, Henriksson Roger, Holgersson Georg, Bergström Stefan, Estenberg Jimmy, Augustsson Torsten, Bergqvist Michael
机构信息
Center for Research and Development, Uppsala University/County Council of Gävleborg, Gävle Hospital, Gävle, Sweden.
Department of Radiation Sciences and Oncology, Umeå University, Umeå, Sweden.
出版信息
Anticancer Res. 2019 Feb;39(2):791-796. doi: 10.21873/anticanres.13176.
BACKGROUND/AIM: The main objective of this study was to evaluate if there was an increased incidence of brain tumours between years 1980-2012, a time period when mobile phone usage has increased substantially.
MATERIALS AND METHODS
From the Swedish Cancer Registry, cases of meningiomas, low-grade gliomas (LGG) and high-grade gliomas (HGG) were identified in patients between 1980-2012. Direct age-standardised incidence rates were used to calculate incidence trends over time.
RESULTS
A total of 13,441 cases of meningiomas, 12,259 cases of high-grade gliomas and 4,555 cases of LGG were reported to the register during the study period. The results suggest that there may be a negative development in the trend for LGG of -0,016 cases per 100,000 and year, corresponding to a mean reduction of approximately 1% per year.
CONCLUSION
The present study was not able to demonstrate an increased incidence of glioma during the past 30 years in Sweden.
背景/目的：本研究的主要目的是评估在1980年至2012年期间（这一时期手机使用量大幅增加）脑肿瘤发病率是否上升。
材料与方法
从瑞典癌症登记处识别出1980年至2012年期间患有脑膜瘤、低级别胶质瘤（LGG）和高级别胶质瘤（HGG）的患者病例。采用直接年龄标准化发病率来计算随时间变化的发病趋势。
结果
在研究期间，登记处共报告了13441例脑膜瘤病例、12259例高级别胶质瘤病例和4555例低级别胶质瘤病例。结果表明，低级别胶质瘤的发病趋势可能呈负增长，每10万人每年减少0.016例，相当于每年平均减少约1%。
结论
本研究未能证明过去30年瑞典胶质瘤发病率上升。
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