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一种小型非接合质粒编码痢疾志贺氏菌的链霉素抗性特征。

A small nonconjugative plasmid encoded for streptomycin-resistant character in Shigella dysenteriae.

作者信息

Datta S, Pal S C, Chaudhuri D K, Kumar R

机构信息

National Institute of Cholera and Enteric Diseases, Calcutta, India.

出版信息

Folia Microbiol (Praha). 1988;33(6):525-8. doi: 10.1007/BF02925781.

DOI:10.1007/BF02925781
PMID:3071516
Abstract

Conjugative transfers of drug-resistant plasmids in Shigella dysenteriae type 1 isolated from the epidemic in West Bengal were unsuccessful. The plasmids were non-transmissible in spite of having the fertility factor F, genetically labelled with kanamycin-resistant transposon Tn903 (pWS 7). A small 2.5 kb nonconjugative plasmid encoded for the streptomycin-resistant character. Cured plasmid-less strains of S. dysenteriae 1 showed resistance to sulfonamides.

摘要

从西孟加拉邦疫情中分离出的1型痢疾志贺菌中,耐药质粒的接合转移未成功。尽管这些质粒具有可育性因子F,并通过卡那霉素抗性转座子Tn903进行了基因标记(pWS 7),但它们仍不可转移。一个2.5 kb的小型非接合性质粒编码了链霉素抗性特征。1型痢疾志贺菌的无质粒治愈菌株对磺胺类药物表现出抗性。

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2
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引用本文的文献

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Expression of virulence and antibiotic resistance in an Escherichia coli transconjugant carrying a large plasmid pCAT120 of Shigella dysenteriae type I and its spontaneous fragmentations.携带痢疾志贺氏菌I型大质粒pCAT120的大肠杆菌转接合子中毒力和抗生素抗性的表达及其自发片段化
Folia Microbiol (Praha). 1991;36(2):127-35. doi: 10.1007/BF02814490.

本文引用的文献

1
Genetic transformation.遗传转化
Annu Rev Biochem. 1981;50:41-68. doi: 10.1146/annurev.bi.50.070181.000353.
2
Epidemic bacillary dysentery in West Bengal, India, 1984.1984年印度西孟加拉邦的流行性杆菌痢疾
Lancet. 1984 Jun 30;1(8392):1462. doi: 10.1016/s0140-6736(84)91948-2.
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Plasmid characterisation in the investigation of an epidemic caused by multiply resistant Shigella dysenteriae type 1 in Central Africa.在中非由多重耐药性1型痢疾志贺菌引起的疫情调查中的质粒特征分析
Lancet. 1981 Nov 14;2(8255):1074-6. doi: 10.1016/s0140-6736(81)91277-0.
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A multiple plasmid-containing Escherichia coli strain: convenient source of size reference plasmid molecules.一种含有多个质粒的大肠杆菌菌株:大小参考质粒分子的便捷来源。
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