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一种小型非接合质粒编码痢疾志贺氏菌的链霉素抗性特征。

A small nonconjugative plasmid encoded for streptomycin-resistant character in Shigella dysenteriae.

作者信息

Datta S, Pal S C, Chaudhuri D K, Kumar R

机构信息

National Institute of Cholera and Enteric Diseases, Calcutta, India.

出版信息

Folia Microbiol (Praha). 1988;33(6):525-8. doi: 10.1007/BF02925781.

Abstract

Conjugative transfers of drug-resistant plasmids in Shigella dysenteriae type 1 isolated from the epidemic in West Bengal were unsuccessful. The plasmids were non-transmissible in spite of having the fertility factor F, genetically labelled with kanamycin-resistant transposon Tn903 (pWS 7). A small 2.5 kb nonconjugative plasmid encoded for the streptomycin-resistant character. Cured plasmid-less strains of S. dysenteriae 1 showed resistance to sulfonamides.

摘要

从西孟加拉邦疫情中分离出的1型痢疾志贺菌中,耐药质粒的接合转移未成功。尽管这些质粒具有可育性因子F,并通过卡那霉素抗性转座子Tn903进行了基因标记(pWS 7),但它们仍不可转移。一个2.5 kb的小型非接合性质粒编码了链霉素抗性特征。1型痢疾志贺菌的无质粒治愈菌株对磺胺类药物表现出抗性。

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