Department of Biomedical and Clinical Science "Luigi Sacco", Eye Clinic, Luigi Sacco Hospital, University of Milan, Milan, Italy.
Save Sight Institute, University of Sydney, Sydney, New South Wales, Australia.
Clin Exp Ophthalmol. 2019 Apr;47(3):357-371. doi: 10.1111/ceo.13470. Epub 2019 Mar 3.
Optical coherence tomography (OCT) has dramatically changed the understanding and management of uveitis and other ocular conditions. Currently, OCT angiography (OCTA) combines structural information with the visualization of blood flow within the imaged area. The aim of this review is to present the basic principles of OCT and OCTA interpretation and to investigate the role of these imaging techniques in the diagnosis and management of uveitis. Common complications of intraocular inflammation such as macular oedema and inflammatory choroidal neovascularization are often diagnosed and followed with OCT/OCTA scans. However, uveitis specialists can obtain much more information from tomographic scans. This review provides a comprehensive description of typical OCT/OCTA findings characterizing different ocular structures in uveitis, proceeding from the cornea to the choroid. A careful interpretation of OCT/OCTA images can help in the differential diagnosis, the prediction of clinical outcomes, and the follow-up of patients with uveitis.
光学相干断层扫描（OCT）极大地改变了人们对葡萄膜炎和其他眼部疾病的认识和治疗方式。目前，OCT 血管造影（OCTA）将结构信息与成像区域内血流的可视化相结合。本综述旨在介绍 OCT 和 OCTA 解读的基本原理，并探讨这些成像技术在葡萄膜炎诊断和管理中的作用。常见的眼内炎症并发症，如黄斑水肿和炎症性脉络膜新生血管形成，通常通过 OCT/OCTA 扫描进行诊断和随访。然而，葡萄膜炎专家可以从断层扫描中获得更多信息。本综述全面描述了在葡萄膜炎中不同眼部结构的典型 OCT/OCTA 表现，从角膜到脉络膜。仔细解读 OCT/OCTA 图像有助于鉴别诊断、预测临床结果以及随访葡萄膜炎患者。
