Hlebowicz Maria, Parczewski Miłosz, Jakubowski Paweł
1 Department of Infectious Diseases, Medical University of Gdansk, Gdansk, Poland.
2 Department of Infectious, Tropical Diseases and Immune Deficiency, Pomeranian Medical University, Szczecin, Poland.
Int J STD AIDS. 2019 May;30(6):617-619. doi: 10.1177/0956462418824905. Epub 2019 Feb 5.
We present the case of a 52-year-old man with human immunodeficiency virus (HIV) encephalitis resulting from cerebrospinal fluid (CSF) viral escape, to illustrate therapeutic challenges in patients with emergent CSF genotypic HIV drug resistance. This case report highlights the usefulness of CSF HIV-resistance testing to guide antiretroviral therapy and treatment optimizing decisions.
我们报告一例52岁男性因脑脊液（CSF）病毒逃逸导致人类免疫缺陷病毒（HIV）脑炎的病例，以说明出现CSF基因型HIV耐药患者的治疗挑战。本病例报告强调了CSF HIV耐药性检测在指导抗逆转录病毒治疗和治疗优化决策方面的作用。
