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技术说明:矿物油、硅油和甘油在 0.35、1.5 和 3 T 时的 T 和 T 及复介电常数。

Technical Note: T and T and complex permittivities of mineral oil, silicone oil, and glycerol at 0.35, 1.5, and 3 T.

机构信息

Departments of Radiation Oncology, Radiology, and Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, 63110, USA.

出版信息

Med Phys. 2019 Apr;46(4):1785-1792. doi: 10.1002/mp.13429. Epub 2019 Feb 18.

Abstract

PURPOSE

To identify an inexpensive, low-dielectric liquid for large magnetic resonance imaging (MRI) phantoms that can be used at multiple magnetic field strengths.

METHODS

The T and T of four candidate phantom liquids (pure mineral oil, food-grade white mineral oil, silicone oil, and glycerol) with low dielectric constants were measured at three field strengths (0.35, 1.5, and 3 T) and extrapolated for 7 T. The complex permittivities of the liquids were measured for frequencies from 13 to 600 MHz. Proton densities were calculated based on molecular weight, proton number, and density. The results were compared to the American College of Radiology (ACR) large MRI phantom electrolyte liquid (10 mM NiCl and 75 mM NaCl in water) and deionized water. The liquids were evaluated based on the NEMA standards (T  < 1200 ms, T  > 50 ms, proton density within 20% of water, and produces minimal dielectric artifacts). The radiofrequency (RF) wavelengths were computed for each liquid at the four field strengths to determine the risk of dielectric artifacts.

RESULTS

The mineral oils were the only liquids to satisfy all of the NEMA guidelines. Excluding deionized water, silicone oil had the longest T and T , and was the most expensive liquid ($200/L). Glycerol had the shortest T and T , and the highest dielectric (excluding the ACR phantom electrolyte and deionized water). All of the liquids except silicone oil met the NEMA proton density guidelines.

CONCLUSIONS

Food-grade white mineral oil is a good candidate for use in a phantom due to its relaxation times, low dielectric, high proton density, and low cost. Glycerol and deionized water are poor choices for phantom liquids due to their relaxation times and high dielectric constants.

摘要

目的

确定一种廉价、低介电常数的液体,用于在多个磁场强度下进行大型磁共振成像(MRI)成像。

方法

在三个磁场强度(0.35、1.5 和 3 T)下测量了四种候选造影剂液体(纯矿物油、食品级白矿物油、硅油和甘油)的 T1 和 T2 值,并外推至 7 T。测量了液体在 13 至 600 MHz 频率下的复介电常数。根据分子量、质子数和密度计算质子密度。将结果与美国放射学院(ACR)大型 MRI 造影剂电解质液体(水中 10 mM NiCl 和 75 mM NaCl)和去离子水进行比较。根据 NEMA 标准(T1 < 1200 ms,T2 > 50 ms,质子密度与水相差 20%以内,产生最小的介电伪影)对液体进行评估。在四个磁场强度下计算了每种液体的射频(RF)波长,以确定介电伪影的风险。

结果

矿物油是唯一满足所有 NEMA 指南的液体。不包括去离子水,硅油具有最长的 T1 和 T2,也是最昂贵的液体(200/L)。甘油具有最短的 T1 和 T2,介电常数最高(不包括 ACR 造影剂电解质和去离子水)。除硅油外,所有液体均符合 NEMA 质子密度指南。

结论

食品级白矿物油是一种很好的造影剂候选物,因为它的弛豫时间短、介电常数低、质子密度高且成本低。甘油和去离子水由于弛豫时间和高介电常数,不适合用作造影剂液体。

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