Clinical Medical College of Fujian Provincial Hospital, Fujian Medical University/Fujian provincial Hospital, Fuzhou, People's Republic of China.
Jiangsu Key Laboratory for Biofunctional Molecules, College of Life Science and Chemistry, Jiangsu Second Normal University, Nanjing, People's Republic of China.
Nat Prod Res. 2020 Jul;34(14):1957-1961. doi: 10.1080/14786419.2019.1569005. Epub 2019 Feb 6.
Pholiotone A (), a new polyketide derivative, with tetrahydrobenzofuran-4(2)-one skeleton, together with four known compounds, trichodermatides A () and B () and koninginins B () and E (), were isolated from the crude extract of sp. The structures of all the isolated compounds were determined mainly by NMR experiments, the modified Mosher method and electronic circular dichroism (ECD) calculations. The antifungal and cytotoxicity of all isolates were evaluated.
Pholiotone A ()，一种新型的聚酮衍生物，具有四氢苯并呋喃-4(2)-酮骨架，与四种已知化合物， Trichodermatides A () 和 B ()以及 koninginins B () 和 E ()一起，从 sp 的粗提物中分离得到。所有分离化合物的结构主要通过 NMR 实验、改良的 Mosher 方法和电子圆二色性 (ECD) 计算来确定。所有分离物的抗真菌和细胞毒性活性均进行了评估。
