Zendehboodi Zahra
Department of Biology, College of Sciences, Shiraz University, Shiraz, 71467-13565 Iran.
J Environ Health Sci Eng. 2018 Sep 12;16(2):337-341. doi: 10.1007/s40201-018-0313-7. eCollection 2018 Dec.
Cookwares made from aluminum (Al) are supposed to be a potential source of Al contamination of food. In this study, the cytotoxicity and genotoxicity effects of water boiled in aluminum cookwares on the dividing cells of onion root tip were examined using assay. Three used aluminum cookwares from different sources were selected. Distilled water was gently boiled in each pot and then used for growing onions. The cells of root tip were analyzed for mitotic and phase indexes as well as aberrations appeared in the interphase and mitotic phase. One way analysis of variance and post-hoc HSD test were applied for comparison between experimental groups. The results showed that the mitotic index in one of the treated groups increased significantly compared to the control. Also the frequency of prophase in two of treated groups increased significantly compared to that of the control. There was a borderline significant increase in the frequency average of total aberrations from three treated groups compared to that of the control ( value = 0.063). Also, a significant increase was observed in the frequency average of disturbed mitosis from three treated groups compared to that of the control ( value = 0.04). The findings of this preliminary study supported a possible health hazard of aluminum cookwares. Further investigation with larger sample and food with various compositions is needed to reach a full conclusion about the health effect of aluminum cookwares.
由铝（Al）制成的炊具被认为是食物铝污染的一个潜在来源。在本研究中，使用[具体检测方法]检测了在铝制炊具中煮沸的水对洋葱根尖分裂细胞的细胞毒性和遗传毒性作用。选择了三个来源不同的二手铝制炊具。在每个锅中用蒸馏水轻轻煮沸，然后用于种植洋葱。分析根尖细胞的有丝分裂和分期指数以及在间期和有丝分裂期出现的畸变。应用单因素方差分析和事后HSD检验对实验组进行比较。结果表明，其中一个处理组的有丝分裂指数与对照组相比显著增加。另外，两个处理组的前期频率与对照组相比也显著增加。三个处理组的总畸变频率平均值与对照组相比有临界显著增加（P值 = 0.063）。此外，三个处理组的有丝分裂紊乱频率平均值与对照组相比有显著增加（P值 = 0.04）。这项初步研究的结果支持了铝制炊具可能存在健康危害的观点。需要用更大的样本和各种成分的食物进行进一步调查，以全面得出关于铝制炊具对健康影响的结论。
