日本孕妇淋病奈瑟菌宫颈炎的现状。
Current status of Neisseria gonorrhoeae cervicitis in pregnant women in Japan.
机构信息
Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, Tokyo, JAPAN.
Japan Association of Obstetricians and Gynecologists, Tokyo, JAPAN.
出版信息
PLoS One. 2019 Feb 7;14(2):e0211595. doi: 10.1371/journal.pone.0211595. eCollection 2019.
We evaluated the current prevalence of gonococcal cervicitis among pregnant women in institutes that either do or do not routinely screen for gonococcal infection in Japan. We requested 2,330 obstetrical facilities to provide information on Neisseria gonorrhoeae cervicitis in pregnant women. A total of 1,876 (80.5%) of them responded. The universal screening test for gonococcal cervicitis, involving nucleic acid amplification for all pregnant women, was performed in 281 institutes (13.9% of institutes across Japan). The total rate of pregnant women with gonococcal cervicitis was 1.3% in the institutes performing the screening test during pregnancy, while it was only 0.2% (p < 0.01) in those not performing it. This suggests that 84% of infected women may have been missed in the institutes that do not routinely perform the screening test for gonococcal cervicitis. It may be time to examine the cost-effectiveness of providing gonococcal screening for all pregnant women in Japan.
我们评估了日本那些常规筛查淋病奈瑟菌感染的医疗机构与不常规筛查的医疗机构中孕妇淋病奈瑟菌宫颈炎的当前流行率。我们要求 2330 家产科机构提供有关孕妇淋病奈瑟菌宫颈炎的信息。共有 1876 家（占日本所有机构的 80.5%）做出了回应。在 281 家机构（占日本机构的 13.9%）中对所有孕妇进行了淋病奈瑟菌宫颈炎的通用筛查检测，即核酸扩增检测。在进行孕期筛查检测的机构中，孕妇淋病奈瑟菌宫颈炎的总发生率为 1.3%，而未进行筛查检测的机构中仅为 0.2%（p<0.01）。这表明，在不常规进行淋病奈瑟菌宫颈炎筛查检测的机构中，可能有 84%的感染女性被漏诊。也许是时候在日本评估为所有孕妇提供淋病筛查的成本效益了。
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