Department of Microbiology, Faculty of Medicine, Kuwait University, P. O. Box 24923, 1311, Safat, Kuwait.
Mycopathologia. 2019 Apr;184(2):303-308. doi: 10.1007/s11046-019-0318-5. Epub 2019 Feb 8.
Fusarium petroliphilum is a recently described species within the Fusarium solani species complex. Some strains of Fusarium species are capable of forming yeast-like structures in tissue as well as in culture through a process known as "adventitious sporulation." Here, we describe the formation of these yeast-like reproductive structures in infected nail tissue obtained from a case of onychomycosis. These structures were also observed in culture grown on RPMI 1640 agar supplemented with 2% glucose. The isolate was resistant to azoles and echinocandins. To the best of our knowledge, this is the first report describing adventitious sporulation in F. petroliphilum and its etiologic role in onychomycosis.
尖孢镰刀菌是尖孢镰刀菌复合种中最近描述的一个物种。一些镰刀菌菌株能够在组织和培养中通过一种称为“偶然孢子形成”的过程形成酵母样结构。在这里，我们描述了从一例甲真菌病中获得的感染指甲组织中这些酵母样生殖结构的形成。在补充有 2%葡萄糖的 RPMI 1640 琼脂上培养时也观察到了这些结构。该分离株对唑类和棘白菌素类药物具有耐药性。据我们所知，这是首次描述尖孢镰刀菌中的偶然孢子形成及其在甲真菌病中的病因作用。
