Postgraduate Program in Movement Sciences, Sao Paulo State University, UNESP, Rio Claro, Brazil.
Department of Physical Therapy, UNESP, Presidente Prudente - SP, Brazil.
J Clin Sleep Med. 2019 Feb 15;15(2):215-221. doi: 10.5664/jcsm.7620.
Sleep is a behavior with the potential to affect cardiovascular health. Given the fact that adiposity and physical activity seem to be related to cardiovascular risk factors during growth, it is still unclear whether sleep quality could affect arterial thickness among adolescents. Thus, the objective of the current study was to analyze the effect of sleep quality on arterial thickness and identify the possible mediation role of physical activity and trunk fat in adolescents.
This was a longitudinal study (12-month follow-up) composed of 71 adolescents with ages ranging from 11 to 14 years at baseline (absence of any known chronic diseases, and no regular medicine use). All variables were assessed twice (baseline and 12-month follow-up): (1) sleep quality was reported using the Mini Sleep Questionnaire (MSQ); (2) physical activity was estimated using pedometers; (3) trunk fat was assessed using a densitometry scanner; and (4) carotid intima-media thickness (CIMT) and femoral intima-media thickness (FIMT) were assessed using ultrasonography.
Adolescents who presented poor sleep quality demonstrated significantly increased FIMT ( = .299, 95% confidence interval .071 to .498) and for every point increase in the MSQ score from baseline to follow-up there was a 1.12% (95% confidence interval 0.26 to 1.98) increase in FIMT over time. Moreover, trunk fat and physical activity did not mediate the association between sleep quality and arterial thickness, but FIMT had a positive and independent relationship only with trunk fat.
Sleep quality was positively associated with FIMT among adolescents, whereas physical activity and adiposity did not mediate this process.
睡眠是一种可能影响心血管健康的行为。鉴于肥胖和体力活动似乎与生长过程中的心血管危险因素有关，目前尚不清楚睡眠质量是否会影响青少年的动脉壁厚度。因此，本研究的目的是分析睡眠质量对动脉壁厚度的影响，并确定体力活动和躯干脂肪在青少年中的可能中介作用。
这是一项纵向研究（12 个月的随访），包括 71 名年龄在 11 至 14 岁的青少年（无任何已知的慢性疾病，且无规律用药）。所有变量均在两次评估（基线和 12 个月的随访）：（1）使用 Mini Sleep Questionnaire（MSQ）报告睡眠质量；（2）使用计步器评估体力活动；（3）使用密度扫描仪评估躯干脂肪；（4）使用超声检查评估颈动脉内膜中层厚度（CIMT）和股动脉内膜中层厚度（FIMT）。
睡眠质量差的青少年 FIMT 显著增加（ =.299，95%置信区间.071 至.498），并且从基线到随访，MSQ 评分每增加 1 分，FIMT 随时间增加 1.12%（95%置信区间 0.26 至 1.98）。此外，躯干脂肪和体力活动并不能中介睡眠质量与动脉厚度之间的关系，但 FIMT 仅与躯干脂肪呈正相关且独立相关。
睡眠质量与青少年的 FIMT 呈正相关，而体力活动和肥胖不能介导这一过程。
