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Meta-analytic studies of the glial cell marker TSPO in psychosis - a question of apples and pears?

作者信息

Plavén-Sigray P, Cervenka S

机构信息

Department of Clinical Neuroscience,Centre for Psychiatry Research, Karolinska Institutet & Stockholm Health Care Services, Stockholm County Council, Karolinska University Hospital,SE-171 76 Stockholm,Sweden.

出版信息

Psychol Med. 2019 Jul;49(10):1624-1628. doi: 10.1017/S003329171800421X. Epub 2019 Feb 11.

DOI:10.1017/S003329171800421X
PMID:30739609
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6601355/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e67c/6601355/630cf24dd3c0/S003329171800421X_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e67c/6601355/ea1a5c284cc0/S003329171800421X_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e67c/6601355/630cf24dd3c0/S003329171800421X_fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e67c/6601355/ea1a5c284cc0/S003329171800421X_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e67c/6601355/630cf24dd3c0/S003329171800421X_fig2.jpg

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本文引用的文献

1
We need to talk about reliability: making better use of test-retest studies for study design and interpretation.我们需要谈谈可靠性：在研究设计和解读中更好地利用重测研究。
PeerJ. 2019 May 24;7:e6918. doi: 10.7717/peerj.6918. eCollection 2019.
2
Accuracy and reliability of [C]PBR28 specific binding estimated without the use of a reference region.不使用参考区域估计 [C]PBR28 特异性结合的准确性和可靠性。
Neuroimage. 2019 Mar;188:102-110. doi: 10.1016/j.neuroimage.2018.11.020. Epub 2018 Nov 27.
3
Test-retest reliability and convergent validity of (R)-[C]PK11195 outcome measures without arterial input function.
Eur J Nucl Med Mol Imaging. 2021 Dec;49(1):164-173. doi: 10.1007/s00259-021-05308-0. Epub 2021 Mar 18.
4
Cellular sources of TSPO expression in healthy and diseased brain.健康和患病大脑中 TSPO 表达的细胞来源。
Eur J Nucl Med Mol Imaging. 2021 Dec;49(1):146-163. doi: 10.1007/s00259-020-05166-2. Epub 2021 Jan 12.
5
Neuroinflammation in psychiatric disorders: PET imaging and promising new targets.精神疾病中的神经炎症：PET 成像与有前景的新靶点。
Lancet Psychiatry. 2020 Dec;7(12):1064-1074. doi: 10.1016/S2215-0366(20)30255-8. Epub 2020 Oct 21.
6
Perspective: Solving the Heterogeneity Conundrum of TSPO PET Imaging in Psychosis.观点：解决精神病中TSPO PET成像的异质性难题。
Front Psychiatry. 2020 May 1;11:362. doi: 10.3389/fpsyt.2020.00362. eCollection 2020.
7
Clinical brain PET research must embrace multi-centre collaboration and data sharing or risk its demise.临床脑PET研究必须采用多中心合作与数据共享，否则可能走向消亡。
Eur J Nucl Med Mol Imaging. 2020 Feb;47(2):502-504. doi: 10.1007/s00259-019-04541-y. Epub 2019 Nov 12.
无动脉输入函数的(R)-[C]PK11195结果测量的重测信度和收敛效度。
EJNMMI Res. 2018 Nov 29;8(1):102. doi: 10.1186/s13550-018-0455-8.
4
Neuroinflammation in schizophrenia: meta-analysis of microglial imaging studies.精神分裂症中的神经炎症：小胶质细胞成像研究的荟萃分析。
Psychol Med. 2019 Oct;49(13):2186-2196. doi: 10.1017/S0033291718003057. Epub 2018 Oct 25.
5
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Biol Psychiatry. 2018 Sep 15;84(6):433-442. doi: 10.1016/j.biopsych.2018.02.1171. Epub 2018 Mar 6.
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J Nucl Med. 2018 Aug;59(8):1267-1274. doi: 10.2967/jnumed.117.203315. Epub 2018 Jan 11.
8
Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry.重新将 translocator protein 概念化为精神病学中神经炎症的生物标志物。
Mol Psychiatry. 2018 Jan;23(1):36-47. doi: 10.1038/mp.2017.232. Epub 2017 Dec 5.
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The macrophage marker translocator protein (TSPO) is down-regulated on pro-inflammatory 'M1' human macrophages.巨噬细胞标志物转位蛋白（TSPO）在促炎性“M1”型人类巨噬细胞上表达下调。
PLoS One. 2017 Oct 2;12(10):e0185767. doi: 10.1371/journal.pone.0185767. eCollection 2017.
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PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia.正电子发射断层扫描成像技术探测处于精神病超高危状态、近期诊断为精神分裂症及慢性精神分裂症患者的疑似小胶质细胞激活。
Transl Psychiatry. 2017 Aug 29;7(8):e1225. doi: 10.1038/tp.2017.193.