Ji N, Wang L J, Liu S W, Liu M, Zeng X Y, Zhou M G
Division of Health Promotion and Intervention, National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Division of Vital Registry and Mortality Surveillance, National Center for Chronic and Non- communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100050, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2019 Feb 10;40(2):160-164. doi: 10.3760/cma.j.issn.0254-6450.2019.02.007.
To assess the disease burden on uterine fibroids in China in 1990 and 2016. Data were extracted from the Global Burden of Disease Study 2016. Burdens of uterine fibrosis among different age groups and provinces were measured in 1990 and 2016, with key indicators including number of cases, prevalence rates, disability-adjusted life year (DALY) and the rates of DALY. The WHO world standard population, 2010-2035 was used to calculate the age- standardized rates. In 1990 and 2016, there were 13 695 567 and 27 169 312 women aged 15 years and older, suffered from uterine fibrosis respectively, with prevalence rate as 2.48% and 4.10%, DALY as 146 045.05 life years and 281 976.67 life years, and the DALY rate as 26.40/100 000 and 42.50/100 000, in 1990 and 2016 respectively. Both the prevalence rate and the DALY rate increased with age, reaching the peak on the 45-49 years-old, in both 1990 and 2016. Women aged 40-54 years accounted for 55.60% (1990) and 66.74% (2016) of the total cases while 48.37% (1990) and 60.65% (2016) of the total DALY. The first three provinces with highest DALYs were Shandong (1990: 12 574.67 life year; 2016: 22 728.12 life year), Henan (1990: 10 849.29 life year; 2016: 18 454.32 life year) and Jiangsu (1990: 10 501.55 life year; 2016: 18 274.10 life year), while the three provinces with leading standardized DALY rates were Heilongjiang (1990: 48.20/100 000; 2016: 47.00/100 000), Shanxi (1990: 44.50/100 000; 2016: 47.70/100 000) and Tianjin (1990: 43.80/100 000; 2016: 46.40/100 000) in both 1990 and 2016. Compared with 1990, the number of cases with uterine fibroids increased by 13 473 745 (with rate of change as: 98.38%), standardized prevalence rate increased by 1.88%, DALY value increased by 135 931.62 life years (with the rate of change as 93.08%) and standardized DALY rate increased by 5.92% among Chinese women, in 2016. Menopausal women were the ones hard hit by uterine fibrosis. Compared with data from 1990, the disease burden of uterine fibrosis increased rapidly in China, in 2016.
评估1990年和2016年中国子宫肌瘤的疾病负担。数据取自《2016年全球疾病负担研究》。测量了1990年和2016年不同年龄组和省份的子宫纤维化负担，关键指标包括病例数、患病率、伤残调整生命年（DALY）和DALY率。使用2010 - 2035年的世界卫生组织世界标准人口来计算年龄标准化率。1990年和2016年，分别有13695567名和27169312名15岁及以上的女性患有子宫纤维化，患病率分别为2.48%和4.10%，DALY分别为146045.05生命年和281976.67生命年，DALY率分别为26.40/10万和42.50/10万。在1990年和2016年，患病率和DALY率均随年龄增长而升高，在45 - 49岁达到峰值。40 - 54岁的女性分别占总病例数的55.60%（1990年）和66.74%（2016年），占总DALY的48.37%（1990年）和60.65%（2016年）。1990年和2016年DALY最高的前三个省份分别是山东（1990年：12574.67生命年；2016年：22728.12生命年）、河南（1990年：10849.29生命年；2016年：18454.32生命年）和江苏（1990年：10501.55生命年；2016年：18274.10生命年），而标准化DALY率领先的三个省份在1990年和2016年都是黑龙江（1990年：48.20/10万；2016年：47.00/10万）、山西（1990年：44.50/10万；2016年：47.70/10万）和天津（1990年：43.80/10万；2016年：46.40/10万）。与1990年相比，2016年中国女性子宫肌瘤病例数增加了13473745例（变化率为：98.38%），标准化患病率增加了1.88%，DALY值增加了135931.62生命年（变化率为93.08%），标准化DALY率增加了5.92%。绝经后女性是子宫纤维化的重灾区。与1990年的数据相比，2016年中国子宫纤维化的疾病负担迅速增加。
