Aoyama Yuki, Takahashi Sakuma, Inaba Tomoki, Izumikawa Koichi, Nakamura Satoko
Department of Gastroenterology, Kagawa Prefectural Central Hospital.
Department of Pathology, Kagawa Prefectural Central Hospital.
Nihon Shokakibyo Gakkai Zasshi. 2019;116(2):145-152. doi: 10.11405/nisshoshi.116.145.
A ring-shaped ulcer was observed in the ileum of a 70-year-old male patient with capsule endoscopy of the small intestine performed for detailed investigation of black stools and iron deficiency anemia. Non-steroidal anti-inflammatory drugs (NSAIDs) use in patch form was considered as the etiology. The NSAIDs patches were discontinued, and protective therapy for small intestinal mucosa was initiated. The anemia improved;however, ileus originating from the site of the ulcer required surgical resection. The resected specimen showed no specific pathological findings. Based on the clinical findings, the patient was diagnosed with NSAIDs-induced small intestinal ulcer. The use of NSAIDs patches should be considered as a potential cause of injury to gastrointestinal mucosa.
对一名70岁男性患者进行小肠胶囊内镜检查,以详细调查黑便和缺铁性贫血,结果在其回肠发现一个环形溃疡。病因被认为是使用了贴片形式的非甾体抗炎药(NSAIDs)。停用了NSAIDs贴片,并开始对小肠黏膜进行保护性治疗。贫血症状有所改善;然而,源自溃疡部位的肠梗阻需要手术切除。切除的标本未显示出特定的病理结果。根据临床表现,该患者被诊断为NSAIDs诱导的小肠溃疡。应考虑使用NSAIDs贴片可能是胃肠道黏膜损伤的一个原因。