Dumont Travis M, Bina Robert W
Department of Surgery, Division of Neurosurgery, University of Arizona - Tucson.
J Vasc Interv Neurol. 2018 Nov;10(2):11-14.
Thrombectomy has become established as a successful treatment strategy for ischemic stroke, and consequently, more patients are undergoing this procedure. Due to comorbid conditions, chronic disease states, and advanced age, many patients have anatomy which complicates revascularization, specifically difficult aortic arch anatomy, or tortuous common and internal artery anatomy, or both.
In the present study, these unfavorable anatomic parameters were analyzed for 53 patients undergoing acute thrombectomy for ischemic stroke. Statistical analysis was performed and the outcome TICI scores were compared. 26 of the patients analyzed had features of difficult femoral access.
Difficult arch anatomy was associated with unsuccessful revascularization ( = 0.03, Fisher's exact) with only 53% of patients with this feature having favorable TICI scores. Difficult common carotid access was also associated with unsuccessful revascularization ( = 0.004, Fisher's exact) with 38% success. There was a trend toward significance for unsuccessful revascularization for difficult internal carotid artery access ( = 0.06, Fisher's exact).
Any combination of the aforementioned anatomic parameters was associated with the decreased success of treatment which was an independent predictor in multivariate analysis ( = 0.009). As difficult access anatomy is commonly encountered in patients undergoing emergent thrombectomy, it is important for the treating physician to be prepared and to adapt access strategies to increase the likelihood of successful revascularization.
血栓切除术已成为缺血性卒中的一种成功治疗策略,因此,越来越多的患者正在接受这一手术。由于合并症、慢性疾病状态和高龄,许多患者的解剖结构使血管再通复杂化,特别是主动脉弓解剖结构困难、颈总动脉和颈内动脉解剖结构迂曲或两者皆有。
在本研究中,对53例接受急性缺血性卒中血栓切除术的患者的这些不利解剖参数进行了分析。进行了统计分析并比较了结局TICI评分。所分析的患者中有26例具有股动脉入路困难的特征。
主动脉弓解剖结构困难与血管再通失败相关(P = 0.03,Fisher精确检验),只有53%具有此特征的患者TICI评分良好。颈总动脉入路困难也与血管再通失败相关(P = 0.004,Fisher精确检验),成功率为38%。颈内动脉入路困难导致血管再通失败有显著趋势(P = 0.06,Fisher精确检验)。
上述任何解剖参数组合均与治疗成功率降低相关,这在多变量分析中是一个独立预测因素(P = 0.