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本文引用的文献

1
Surgical resection for advanced lung cancer using the hemi-clamshell approach.采用半蛤壳式入路对晚期肺癌进行手术切除。
Interact Cardiovasc Thorac Surg. 2017 Sep 1;25(3):462-468. doi: 10.1093/icvts/ivx142.
2
Pleuropneumonectomy for a large thymoma with multiple pleural dissemination using median sternotomy followed by posterolateral thoracotomy.采用正中胸骨切开术继以后外侧开胸术对伴有多处胸膜播散的巨大胸腺瘤进行胸膜肺切除术。
Surg Case Rep. 2015;1(1):75. doi: 10.1186/s40792-015-0071-z. Epub 2015 Sep 2.
3
Giant thymoma successfully resected via anterolateral thoracotomy: a case report.经胸壁前外侧切口成功切除巨大胸腺瘤:一例报告
J Cardiothorac Surg. 2015 Sep 1;10:110. doi: 10.1186/s13019-015-0321-y.
4
The IASLC/ITMIG Thymic Epithelial Tumors Staging Project: proposals for the N and M components for the forthcoming (8th) edition of the TNM classification of malignant tumors.IASLC/ITMIG 胸腺上皮肿瘤分期项目:即将发布的(第 8 版)TNM 恶性肿瘤分类中 N 和 M 成分的建议。
J Thorac Oncol. 2014 Sep;9(9 Suppl 2):S81-7. doi: 10.1097/JTO.0000000000000291.
5
Ectopic thymoma presenting as a giant intrathoracic mass: a case report.表现为巨大胸腔内肿块的异位胸腺瘤:一例报告
J Cardiothorac Surg. 2012 Jul 16;7:68. doi: 10.1186/1749-8090-7-68.
6
Does surgical debulking for advanced stages of thymoma improve survival?对于晚期胸腺瘤进行手术减瘤是否能提高生存率?
Interact Cardiovasc Thorac Surg. 2012 Sep;15(3):494-7. doi: 10.1093/icvts/ivs263. Epub 2012 Jun 14.
7
Preservation of phrenic nerve involved by stage III thymoma.胸腺瘤 III 期累及膈神经的保存
Ann Thorac Surg. 2010 May;89(5):1612-9. doi: 10.1016/j.athoracsur.2010.01.057.
8
Giant thymoma in the anterior-inferior mediastinum.前下纵隔巨大胸腺瘤。
Interact Cardiovasc Thorac Surg. 2010 Mar;10(3):451-3. doi: 10.1510/icvts.2009.225557. Epub 2009 Dec 29.
9
Early Masaoka stage and complete resection is important for prognosis of thymic carcinoma: a 20-year experience at a single institution.早期Masaoka分期及完整切除对胸腺癌预后很重要:单机构20年经验
Eur J Cardiothorac Surg. 2009 Jul;36(1):159-62; discussion 163. doi: 10.1016/j.ejcts.2009.02.019. Epub 2009 Mar 25.
10
Clinical and pathological aspects of thymic epithelial tumors.胸腺上皮肿瘤的临床与病理特征
Gen Thorac Cardiovasc Surg. 2008 Jan;56(1):10-6. doi: 10.1007/s11748-007-0177-8. Epub 2008 Jan 22.

采用半蛤壳式入路对伴有肺门侵犯的晚期胸腺恶性肿瘤进行手术切除。

Surgical resection for advanced thymic malignancy with pulmonary hilar invasion using hemi-clamshell approach.

作者信息

Fujiwara Ayako, Funaki Soichiro, Ose Naoko, Kanou Takashi, Kanzaki Ryu, Minami Masato, Shintani Yasushi

机构信息

Department of General Thoracic Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.

出版信息

J Thorac Dis. 2018 Dec;10(12):6475-6481. doi: 10.21037/jtd.2018.11.73.

DOI:10.21037/jtd.2018.11.73
PMID:30746191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6344672/
Abstract

BACKGROUND

The hemi-clamshell (HCS) approach provides a wide anterior view of the mediastinum as well as outstanding exposure of the pulmonary hilum. Here, we evaluated the utility and outcomes of this approach in cases of advanced thymic malignancy with hilar invasion.

METHODS

We performed a retrospective analysis of 14 patients with thymic epithelial malignancy surgically resected with an HCS approach. All required lung resection because of suspected pulmonary hilar vessel invasion.

RESULTS

Histological findings showed that 8 patients had a thymoma and 6 a thymic carcinoma. Thirteen patients underwent lung resection, a lobectomy or bilobectomy in 8 and wedge resection in 5, while 1 had an exploratory thoracotomy. Seven patients with a thymoma underwent resection of disseminated lesions and 8 of 10 who underwent phrenic nerve resection received diaphragmatic plication through an HCS procedure. There were no postoperative mortalities. Macroscopic complete surgical resection was achieved in 13 cases.

CONCLUSIONS

An HCS approach was helpful for lung resection performed for advanced thymic malignancy with hilar invasion by providing multiple access paths to the tumor and hilum, allowing for a sufficient surgical margin. Furthermore, it was useful for resection of disseminated lesions and diaphragmatic plication.

摘要

背景

半蛤壳式(HCS)入路可提供纵隔广泛的前视图以及肺门的良好暴露。在此,我们评估了该入路在伴有肺门侵犯的晚期胸腺恶性肿瘤病例中的实用性和疗效。

方法

我们对14例采用HCS入路手术切除的胸腺上皮恶性肿瘤患者进行了回顾性分析。由于怀疑肺门血管受侵,所有患者均需行肺切除。

结果

组织学检查结果显示,8例为胸腺瘤,6例为胸腺癌。13例患者接受了肺切除,其中8例行肺叶切除术或双肺叶切除术,5例行楔形切除术,1例行开胸探查术。7例胸腺瘤患者接受了播散性病变切除术,10例接受膈神经切除术的患者中有8例通过HCS手术进行了膈肌折叠术。无术后死亡病例。13例实现了宏观上的完全手术切除。

结论

HCS入路通过为肿瘤和肺门提供多条进入路径,有助于对伴有肺门侵犯的晚期胸腺恶性肿瘤进行肺切除,从而获得足够的手术切缘。此外,它对播散性病变的切除和膈肌折叠术也很有用。