• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

英国 2018 年 1 月 1 日至 2019 年 1 月 21 日急性弛缓性麻痹(AFP)报告增多:初步结果。

An increase in reports of acute flaccid paralysis (AFP) in the United Kingdom, 1 January 2018-21 January 2019: early findings.

机构信息

Members of the UK AFP task force are listed at the end of the article.

出版信息

Euro Surveill. 2019 Feb;24(6). doi: 10.2807/1560-7917.ES.2019.24.6.1900093.

DOI:10.2807/1560-7917.ES.2019.24.6.1900093
PMID:30755296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6373064/
Abstract

During 2018, the United Kingdom experienced an increase in reports of cases of acute flaccid paralysis (AFP). As at 21 January 2019, 40 cases had been identified with a peak in October 2018. The increase was temporally associated with an upsurge in enterovirus (EV) D68 activity. Enterovirus was detected in 15 cases, mainly from respiratory tract samples; nine were typed as EV-D68. A national task force has been established and investigations are ongoing.

摘要

2018 年期间,英国报告的急性弛缓性麻痹(AFP)病例有所增加。截至 2019 年 1 月 21 日,已确定 40 例病例,其中 2018 年 10 月达到高峰。这一增长与肠道病毒(EV)D68 活动的激增有关。在 15 例病例中检测到肠道病毒,主要来自呼吸道样本;其中 9 例为 EV-D68 型。已经成立了一个国家工作队,正在进行调查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5139/6373064/19111e945f3b/1900093-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5139/6373064/abfb1b145521/1900093-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5139/6373064/19111e945f3b/1900093-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5139/6373064/abfb1b145521/1900093-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5139/6373064/19111e945f3b/1900093-f2.jpg

相似文献

1
An increase in reports of acute flaccid paralysis (AFP) in the United Kingdom, 1 January 2018-21 January 2019: early findings.英国 2018 年 1 月 1 日至 2019 年 1 月 21 日急性弛缓性麻痹(AFP)报告增多:初步结果。
Euro Surveill. 2019 Feb;24(6). doi: 10.2807/1560-7917.ES.2019.24.6.1900093.
2
Clinical Features of Acute Flaccid Myelitis Temporally Associated With an Enterovirus D68 Outbreak: Results of a Nationwide Survey of Acute Flaccid Paralysis in Japan, August-December 2015.与肠道病毒 D68 暴发相关的急性弛缓性脊髓炎的临床特征:2015 年 8 月至 12 月日本全国急性弛缓性麻痹调查结果。
Clin Infect Dis. 2018 Feb 10;66(5):653-664. doi: 10.1093/cid/cix860.
3
[Acute flaccid myelitis amongst Swedish children with a possible link to an outbreak of enterovirus D68].[瑞典儿童中的急性弛缓性脊髓炎,可能与肠道病毒D68的爆发有关]
Lakartidningen. 2017 Nov 30;114:ETDZ.
4
Enterovirus D68 Infection in Children with Acute Flaccid Myelitis, Colorado, USA, 2014.2014年美国科罗拉多州急性弛缓性脊髓炎患儿的肠道病毒D68感染
Emerg Infect Dis. 2016 Aug;22(8):1387-94. doi: 10.3201/eid2208.151949.
5
Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview.2016 年欧洲 29 例肠道病毒 D68 相关急性弛缓性脊髓炎:病例系列和流行病学概述。
Pediatr Infect Dis J. 2019 Jan;38(1):16-21. doi: 10.1097/INF.0000000000002188.
6
Acute flaccid myelitis associated with enterovirus-D68 infection in an otherwise healthy child.一名原本健康的儿童感染肠道病毒D68后出现急性弛缓性脊髓炎。
Virol J. 2017 Jan 11;14(1):4. doi: 10.1186/s12985-016-0678-0.
7
Pediatric Acute Flaccid Paralysis: Enterovirus D68-Associated Anterior Myelitis.小儿急性弛缓性麻痹:肠道病毒D68相关的脊髓前角灰质炎
J Emerg Med. 2017 Jul;53(1):e19-e23. doi: 10.1016/j.jemermed.2017.03.020. Epub 2017 Apr 12.
8
A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012-14): a retrospective cohort study.美国2012 - 2014年与急性弛缓性脊髓炎病例相关的新型肠道病毒D68毒株:一项回顾性队列研究。
Lancet Infect Dis. 2015 Jun;15(6):671-82. doi: 10.1016/S1473-3099(15)70093-9. Epub 2015 Mar 31.
9
Association of Enterovirus D68 with Acute Flaccid Myelitis, Philadelphia, Pennsylvania, USA, 2009-2018.2009-2018 年美国宾夕法尼亚州费城肠病毒 D68 与急性弛缓性脊髓炎的关联。
Emerg Infect Dis. 2019 Sep;25(9):1676-1682. doi: 10.3201/eid2509.190468. Epub 2019 Sep 17.
10
Enterovirus D68 and acute flaccid myelitis-evaluating the evidence for causality.肠道病毒 D68 和急性弛缓性脊髓炎——评估因果关系的证据。
Lancet Infect Dis. 2018 Aug;18(8):e239-e247. doi: 10.1016/S1473-3099(18)30094-X. Epub 2018 Feb 23.

引用本文的文献

1
Acute flaccid myelitis in Europe between 2016 and 2023: indicating the need for better registration.2016年至2023年间欧洲的急性弛缓性脊髓炎:表明需要更好的登记。
Euro Surveill. 2025 May;30(21). doi: 10.2807/1560-7917.ES.2025.30.21.2400579.
2
VP1 is the primary determinant of neuropathogenesis in a mouse model of enterovirus D68 acute flaccid myelitis.VP1 是肠道病毒 D68 急性弛缓性脊髓炎小鼠模型中神经发病机制的主要决定因素。
J Virol. 2024 Jul 23;98(7):e0039724. doi: 10.1128/jvi.00397-24. Epub 2024 Jun 13.
3
Thirteen-year surveillance results of acute flaccid paralysis cases in Southeast Turkey and the effect of refugee movements on surveillance results.

本文引用的文献

1
Neurotropism of Enterovirus D68 Isolates Is Independent of Sialic Acid and Is Not a Recently Acquired Phenotype.肠道病毒 D68 分离株的神经嗜性独立于唾液酸,并且不是新近获得的表型。
mBio. 2019 Oct 22;10(5):e02370-19. doi: 10.1128/mBio.02370-19.
2
Increase in Acute Flaccid Myelitis - United States, 2018.急性弛缓性脊髓炎病例增多 - 美国,2018 年。
MMWR Morb Mortal Wkly Rep. 2018 Nov 16;67(45):1273-1275. doi: 10.15585/mmwr.mm6745e1.
3
Coxsackievirus B1 resulting acute flaccid myelitis with entire spinal cord lesion: a case report.
土耳其东南部急性弛缓性麻痹病例十三年监测结果及难民流动对监测结果的影响。
Cent Eur J Public Health. 2024 Mar;32(1):45-51. doi: 10.21101/cejph.a7605.
4
Acute flaccid myelitis: not uncommon in rural Uganda?急性弛缓性脊髓炎:在乌干达农村地区并不罕见?
Brain Commun. 2023 Oct 18;5(5):fcad246. doi: 10.1093/braincomms/fcad246. eCollection 2023.
5
Increased reports of severe myocarditis associated with enterovirus infection in neonates, United Kingdom, 27 June 2022 to 26 April 2023.2022 年 6 月 27 日至 2023 年 4 月 26 日期间,英国报告与肠道病毒感染相关的新生儿重度心肌炎病例增多。
Euro Surveill. 2023 Sep;28(39). doi: 10.2807/1560-7917.ES.2023.28.39.2300313.
6
Changes in transmission of Enterovirus D68 (EV-D68) in England inferred from seroprevalence data.从血清流行率数据推断英格兰肠道病毒 D68(EV-D68)传播的变化。
Elife. 2023 Jun 9;12:e76609. doi: 10.7554/eLife.76609.
7
Acute flaccid myelitis associated with enterovirus D68: An emerging infectious disease.与肠道病毒D68相关的急性弛缓性脊髓炎:一种新发传染病。
J Assoc Med Microbiol Infect Dis Can. 2019 Oct 11;4(3):131-135. doi: 10.3138/jammi.2019-03-28. eCollection 2019 Oct.
8
Epidemiology of acute flaccid myelitis in children in the Netherlands, 2014 to 2019.荷兰 2014 年至 2019 年儿童急性弛缓性脊髓炎的流行病学。
Euro Surveill. 2022 Oct;27(42). doi: 10.2807/1560-7917.ES.2022.27.42.2200157.
9
Enterovirus D68 epidemic, UK, 2018, was caused by subclades B3 and D1, predominantly in children and adults, respectively, with both subclades exhibiting extensive genetic diversity.2018 年英国肠道病毒 D68 疫情由亚群 B3 和 D1 引起,分别主要发生在儿童和成人中,两个亚群均表现出广泛的遗传多样性。
Microb Genom. 2022 May;8(5). doi: 10.1099/mgen.0.000825.
10
Global prevalence and case fatality rate of Enterovirus D68 infections, a systematic review and meta-analysis.全球肠道病毒 D68 感染的流行率和病死率:系统评价和荟萃分析。
PLoS Negl Trop Dis. 2022 Feb 8;16(2):e0010073. doi: 10.1371/journal.pntd.0010073. eCollection 2022 Feb.
1型柯萨奇病毒导致的急性弛缓性脊髓炎伴全脊髓病变:一例报告
Neurol Sci. 2019 Mar;40(3):627-629. doi: 10.1007/s10072-018-3607-8. Epub 2018 Oct 19.
4
Contemporary Circulating Enterovirus D68 Strains Have Acquired the Capacity for Viral Entry and Replication in Human Neuronal Cells.当代循环肠道病毒 D68 株已获得在人类神经元细胞中进行病毒进入和复制的能力。
mBio. 2018 Oct 16;9(5):e01954-18. doi: 10.1128/mBio.01954-18.
5
Twenty-nine Cases of Enterovirus-D68-associated Acute Flaccid Myelitis in Europe 2016: A Case Series and Epidemiologic Overview.2016 年欧洲 29 例肠道病毒 D68 相关急性弛缓性脊髓炎:病例系列和流行病学概述。
Pediatr Infect Dis J. 2019 Jan;38(1):16-21. doi: 10.1097/INF.0000000000002188.
6
Acute Flaccid Paralysis and Enteroviral Infections.急性弛缓性麻痹与肠道病毒感染
Curr Infect Dis Rep. 2018 Jun 29;20(9):34. doi: 10.1007/s11908-018-0641-x.
7
Recommendations for enterovirus diagnostics and characterisation within and beyond Europe.推荐在欧洲内外进行肠道病毒诊断和鉴定的建议。
J Clin Virol. 2018 Apr;101:11-17. doi: 10.1016/j.jcv.2018.01.008. Epub 2018 Feb 6.
8
The association between acute flaccid myelitis (AFM) and Enterovirus D68 (EV-D68) - what is the evidence for causation?急性弛缓性脊髓炎(AFM)与肠道病毒 D68(EV-D68)的关联 - 病因证据是什么?
Euro Surveill. 2018 Jan;23(3). doi: 10.2807/1560-7917.ES.2018.23.3.17-00310.
9
Clinical Features of Acute Flaccid Myelitis Temporally Associated With an Enterovirus D68 Outbreak: Results of a Nationwide Survey of Acute Flaccid Paralysis in Japan, August-December 2015.与肠道病毒 D68 暴发相关的急性弛缓性脊髓炎的临床特征:2015 年 8 月至 12 月日本全国急性弛缓性麻痹调查结果。
Clin Infect Dis. 2018 Feb 10;66(5):653-664. doi: 10.1093/cid/cix860.
10
Genetic changes found in a distinct clade of Enterovirus D68 associated with paralysis during the 2014 outbreak.在2014年疫情期间,在与麻痹相关的肠道病毒D68一个独特进化枝中发现的基因变化。
Virus Evol. 2016 Jun 15;2(1):vew015. doi: 10.1093/ve/vew015. eCollection 2016 Jan.