UK Health Security Agency, Colindale, London, United Kingdom.
Public Health Wales, Wales, Cardiff, United Kingdom.
Euro Surveill. 2023 Sep;28(39). doi: 10.2807/1560-7917.ES.2023.28.39.2300313.
Enteroviruses are a common cause of seasonal childhood infections. The vast majority of enterovirus infections are mild and self-limiting, although neonates can sometimes develop severe disease. Myocarditis is a rare complication of enterovirus infection. Between June 2022 and April 2023, twenty cases of severe neonatal enteroviral myocarditis caused by coxsackie B viruses were reported in the United Kingdom. Sixteen required critical care support and two died. Enterovirus PCR on whole blood was the most sensitive diagnostic test. We describe the initial public health investigation into this cluster and aim to raise awareness among paediatricians, laboratories and public health specialists.
肠道病毒是儿童季节性感染的常见病因。绝大多数肠道病毒感染为轻症自限性，但新生儿有时可发生重症疾病。心肌炎是肠道病毒感染的罕见并发症。2022 年 6 月至 2023 年 4 月期间，英国报告了 20 例由柯萨奇 B 病毒引起的严重新生儿肠道病毒心肌炎病例。16 例需要重症监护支持，2 例死亡。全血肠道病毒 PCR 是最敏感的诊断试验。我们描述了对此聚集性病例的初步公共卫生调查，旨在提高儿科医生、实验室和公共卫生专家的认识。
