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基于 Inception 递归残差卷积神经网络的乳腺病理图像分类。

Breast Cancer Classification from Histopathological Images with Inception Recurrent Residual Convolutional Neural Network.

机构信息

Department of Electrical and Computer Engineering, University of Dayton, Dayton, OH, USA.

出版信息

J Digit Imaging. 2019 Aug;32(4):605-617. doi: 10.1007/s10278-019-00182-7.

DOI:10.1007/s10278-019-00182-7
PMID:30756265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6646497/
Abstract

The Deep Convolutional Neural Network (DCNN) is one of the most powerful and successful deep learning approaches. DCNNs have already provided superior performance in different modalities of medical imaging including breast cancer classification, segmentation, and detection. Breast cancer is one of the most common and dangerous cancers impacting women worldwide. In this paper, we have proposed a method for breast cancer classification with the Inception Recurrent Residual Convolutional Neural Network (IRRCNN) model. The IRRCNN is a powerful DCNN model that combines the strength of the Inception Network (Inception-v4), the Residual Network (ResNet), and the Recurrent Convolutional Neural Network (RCNN). The IRRCNN shows superior performance against equivalent Inception Networks, Residual Networks, and RCNNs for object recognition tasks. In this paper, the IRRCNN approach is applied for breast cancer classification on two publicly available datasets including BreakHis and Breast Cancer (BC) classification challenge 2015. The experimental results are compared against the existing machine learning and deep learning-based approaches with respect to image-based, patch-based, image-level, and patient-level classification. The IRRCNN model provides superior classification performance in terms of sensitivity, area under the curve (AUC), the ROC curve, and global accuracy compared to existing approaches for both datasets.

摘要

深度卷积神经网络(DCNN)是最强大和最成功的深度学习方法之一。DCNN 已经在不同的医学成像模式中提供了卓越的性能,包括乳腺癌分类、分割和检测。乳腺癌是全球影响女性最常见和最危险的癌症之一。在本文中,我们提出了一种使用 Inception Recurrent Residual Convolutional Neural Network(IRRCNN)模型进行乳腺癌分类的方法。IRRCNN 是一种强大的 DCNN 模型,它结合了 Inception 网络(Inception-v4)、Residual 网络(ResNet)和 Recurrent Convolutional Neural Network(RCNN)的优势。在对象识别任务中,IRRCNN 相较于等效的 Inception 网络、Residual 网络和 RCNN 表现出卓越的性能。在本文中,IRRCNN 方法应用于两个公开可用的数据集,包括 BreakHis 和 Breast Cancer(BC)classification challenge 2015,进行乳腺癌分类。实验结果与现有的机器学习和基于深度学习的方法进行了比较,包括基于图像、基于补丁、图像级和患者级的分类。与现有方法相比,IRRCNN 模型在两个数据集的敏感性、曲线下面积(AUC)、ROC 曲线和全局准确性方面提供了卓越的分类性能。

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