Laboratory of Natural Product and Organic Synthesis, Department of Chemistry, Univesity Constantine 1, Constantine, Algeria.
Departamento de Química Orgánica, Instituto Universitario de Bio-orgánica "Antonio Gonzalez" Universidad de La Laguna, La Laguna, Spain.
Nat Prod Res. 2020 Nov;34(22):3257-3261. doi: 10.1080/14786419.2018.1556658. Epub 2019 Feb 13.
Many studies demonstrated that Algerian propolis possess a large spectrum of biological activity. However, few studies regarding its chemical composition are available on literature. We aimed in the present study to investigate the chemical composition of Algerian propolis. In addition, the antioxidants and anticholinesterase activities of propolis extracts are also reported. Chemical investigation of Algerian propolis allowed the isolation of 8 compounds. Their structures were identified on the basis of spectral data and comparison with literature. The isolated compounds are considered as markers of poplar and suggesting the use of both species as plant source of the tested propolis. The ethyl acetate extract of the tested propolis demonstrated the highest antioxidant activity. Among the tested extracts, only the petroleum ether and chloroform extracts exhibited an AChE inhibitory activity.
许多研究表明，阿尔及利亚蜂胶具有广泛的生物活性。然而，关于其化学成分的研究在文献中很少见。本研究旨在研究阿尔及利亚蜂胶的化学成分。此外，还报告了蜂胶提取物的抗氧化和抗胆碱酯酶活性。对阿尔及利亚蜂胶的化学研究允许分离出 8 种化合物。根据光谱数据和与文献的比较，确定了它们的结构。分离出的化合物被认为是杨树的标志物，并表明这两个物种都可以作为测试用蜂胶的植物来源。所测试的蜂胶的乙酸乙酯提取物表现出最高的抗氧化活性。在所测试的提取物中，只有石油醚和氯仿提取物表现出 AChE 抑制活性。
