Álvaro-Afonso Francisco Javier, Lázaro-Martínez José Luis, Papanas Nikolaos
1 Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos, Madrid, Spain.
2 Democritus University of Thrace, University Hospital of Alexandroupolis, Alexandroupolis, Greece.
Int J Low Extrem Wounds. 2018 Dec;17(4):258-260. doi: 10.1177/1534734618808168.
Diabetic foot ulcers (DFUs) have a complex pathophysiology and require an expert multidisciplinary treatment. There are several, both systemic and local, risk factors for DFUs. A recent meta-analysis of 18 studies has now provided robust evidence on the detrimental effect of smoking on healing of DFUs. Indeed, healing rates were consistently lower among smokers than among nonsmokers. Based on this new evidence, it is reasonable to consider the utility of smoking cessation programs. Incorporation of the latter into the holistic therapeutic strategy for DFUs may be anticipated to improve healing rates, but this remains to be shown.
糖尿病足溃疡（DFUs）具有复杂的病理生理学，需要专家进行多学科治疗。DFUs存在多种全身和局部危险因素。最近一项对18项研究的荟萃分析现已提供了有力证据，证明吸烟对DFUs愈合具有有害影响。事实上，吸烟者的愈合率始终低于非吸烟者。基于这一新证据，考虑戒烟计划的效用是合理的。将后者纳入DFUs的整体治疗策略中，有望提高愈合率，但这仍有待证实。
