Elkbuli Adel, Yaras Reed, Elghoroury Ahmad, Boneva Dessy, Hai Shaikh, McKenney Mark
Am Surg. 2019 Jan 1;85(1):59-63.
The revised trauma score combined with the Injury Severity Score (ISS) remains the mostly commonly used system for predicting trauma mortality, but these scoring systems do not account for the patient's comorbidities. This study aims to evaluate the effect of comorbidities on ISS-related mortality and length of stay. A review of our trauma center's data registry from 2014 to 2016 was carried out. Patients were divided according to ISS into two groups: ISS ≤ 15 and ISS > 15. Each ISS group was then subdivided by number of comorbidities into two groups: 1 to 2 or ≥3 comorbidities. Demographic characteristics and outcome measures were compared. ANOVA, chi-squared, and tests were used with significance defined as < 0.05. A total 9845 adult trauma patients were admitted to our trauma center during the three-year study period. In the ISS ≤ 15 group, patients with <3 comorbidities had significantly higher mortality rate compared with patients with 1 to 2 comorbidities (1.50% 0.12%, ≪ 0.000007). Comparing the ISS ≤ 15 group with ≥3 comorbidities with the ISS > 15 group with 1 to 2 comorbidities, the mortality rate was significantly higher (23.40% 4.50%, ≪ 0.000002). The ICU length of stay was significantly higher in the ISS ≤ 15 groups (17 10 days, < 0.05) but similar in the ISS > 15 groups (31 29 days) ( > 0.05). It was concluded that when controlling for injury severity, increased comorbidities are associated with a significantly higher mortality, indicating that they may serve as a marker of lower physiologic reserve and be an independent variable. Adding comorbidity parameters to the current trauma scoring systems can assist in predicting more accurate/reliable outcomes.
修订后的创伤评分与损伤严重程度评分(ISS)相结合,仍然是预测创伤死亡率最常用的系统,但这些评分系统并未考虑患者的合并症。本研究旨在评估合并症对与ISS相关的死亡率和住院时间的影响。对我们创伤中心2014年至2016年的数据登记进行了回顾。患者根据ISS分为两组:ISS≤15和ISS>15。然后,每个ISS组再根据合并症数量细分为两组:1至2种合并症或≥3种合并症。比较了人口统计学特征和结局指标。使用方差分析、卡方检验和t检验,显著性定义为P<0.05。在为期三年的研究期间,共有9845名成年创伤患者入住我们的创伤中心。在ISS≤15组中,合并症<3种的患者死亡率显著高于合并症为1至2种的患者(1.50%对0.12%,P≪0.000007)。将ISS≤15且合并症≥3种的组与ISS>15且合并症为1至2种的组进行比较,死亡率显著更高(23.40%对4.50%,P≪0.000002)。ISS≤15组的重症监护病房住院时间显著更长(17对10天,P<0.05),但ISS>15组相似(31对29天)(P>0.05)。得出的结论是,在控制损伤严重程度时,合并症增加与显著更高的死亡率相关,表明它们可能作为生理储备较低的标志物,并且是一个独立变量。在当前的创伤评分系统中添加合并症参数有助于预测更准确/可靠的结局。