初乳免疫球蛋白和氧化能力可能受婴儿性别、母亲年龄和产次的影响。
Colostrum immunoglobulins and oxidative capacity may be affected by infant sex and maternal age and parity.
出版信息
Turk J Med Sci. 2019 Feb 11;49(1):87-92. doi: 10.3906/sag-1810-66.
BACKGROUND/AIM: The aims of this study were to determine the levels of the total antioxidant status (TAS), the total oxidant status (TOS), the oxidative stress index (OSI), and the concentration of immunoglobulin A (IgA) and M (IgM) in colostrum, and evaluate relationships between these parameters and maternal age, maternal parity, and infant sex.
MATERIALS AND METHODS
The analysis was performed in serum samples of colostrum which were collected from 90 mothers on the first day of lactation between 10:00 and 12:00 AM
RESULTS
The measurements established that no significant association existed between the TAS level of colostrum and parity, maternal age, or infant sex. However, mothers 18 to 30 years of age had significantly lower colostrum TOS and OSI levels compared with mothers older than 30 years of age. IgA and IgM values of the colostrum of primiparous mothers were significantly higher than those of multiparous mothers, whereas no correlations existed with the age of the mother. Additionally, significantly higher colostrum IgA and IgM values were observed in female infants fed colostrum compared with male infants.
CONCLUSION
In conclusion, sex-based hormonal changes in mothers during pregnancy may be associated with the different colostral immunoglobulin levels for male and female infants.
背景/目的：本研究旨在确定初乳中总抗氧化状态（TAS）、总氧化状态（TOS）、氧化应激指数（OSI）以及免疫球蛋白 A（IgA）和 M（IgM）的浓度，并评估这些参数与母亲年龄、母亲产次和婴儿性别之间的关系。
材料和方法
在哺乳期的第一天上午 10 点至 12 点之间，从 90 位母亲的初乳中采集血清样本进行分析。
结果
测量结果表明，初乳的 TAS 水平与产次、母亲年龄或婴儿性别之间没有显著关联。然而，18 至 30 岁的母亲的初乳 TOS 和 OSI 水平明显低于 30 岁以上的母亲。初乳中初产妇的 IgA 和 IgM 值明显高于多产妇，而与母亲的年龄无关。此外，与男婴相比，女性婴儿喂养的初乳中 IgA 和 IgM 值明显更高。
结论
综上所述，母亲在怀孕期间基于性别的激素变化可能与男婴和女婴的不同初乳免疫球蛋白水平有关。
Zotero 插件